Abstract: The present invention concerns a handheld apparatus for automated and directional disengagement of a dose unit (17), such as a pill from its packaging (16), said apparatus comprising a housing (2) having a first and second end, where the housing is provided with an opening for receiving and supporting a packaging and positioning of a dose unit in this packaging and holding means arranged adjacent to said opening of the second end; and expelling means comprising a plunger (5) which by actuation of drive means (1) can be pushed against the holding means and hereby having a dose unit disengaged. The advantage of this dispenser apparatus is that it automatically causes the pill to be disengaged from the blister pack, reducing the working environment problems by reducing the repetitive one-sided manual work load, and reducing contamination risks by directional placement of the dose unit.