Patents Assigned to Pisgah National Laboratories, Inc.
  • Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief
    Publication number: 20130338229
    Abstract: Provided is a drug substance and a method of treating an ailment comprising administering an oral dose of a drug product comprising the drug substance wherein the drug substance comprises an organic acid addition salt of methadone. The organic acid addition salt is selected from the group consisting of pamoate and xinafoate wherein the drug substance is bioavailable under gastrointestinal administration but is not bioavailable under administration at a mucosal membrane other than gastrointestinal or release from a depot injectable product.
    Type: Application
    Filed: July 29, 2013
    Publication date: December 19, 2013
    Applicant: Pisgah National Laboratories, Inc.
    Inventors: Clifford Riley King, Stephen G. D'Ambrosio, David William Bristol, Michael L. English
  • Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
    Patent number: 8575151
    Abstract: Drug substances comprising a pharmaceutically acceptable organic acid addition salt of amine containing pharmaceutically active compounds useful for the treatment of a therapeutic ailment administration and exhibiting prophylactic properties when employed in non-therapeutic administration.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: November 5, 2013
    Assignee: Pisgah National Laboratories, Inc.
    Inventors: David William Bristol, Clifford Riley King, Joseph Pike Mitchener, Jr., Vicki Haynes Audia