Abstract: The present disclosure relates to novel platinum compositions having a heterocycle ligand and nanoparticles and methods using such compositions, e.g. for treating cancer.
Type:
Grant
Filed:
August 24, 2017
Date of Patent:
November 12, 2019
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Adam H. Brockman, Mark T. Bilodeau, Benoît Moreau, Edward R. Lee
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
Type:
Grant
Filed:
June 22, 2016
Date of Patent:
July 9, 2019
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Rossitza G. Alargova, Mark T. Bilodeau, Richard Wooster, Benoît Moreau, Kerry Whalen, J. Michael Ramstack, Danielle N. Rockwood, Patrick Lim Soo, Sukhjeet Singh, Tsun P. Au Yeung, Charles-Andre Lemelin, Linda M. Custer
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
Type:
Grant
Filed:
September 21, 2017
Date of Patent:
June 18, 2019
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Mark T. Bilodeau, Benoit Moreau, Adam H. Brockman, Kristan Meetze, Kerry Whalen, Richard Wooster, Rossitza G. Alargova
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one polar moiety as a ligand.
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one carboxylate or carbamate ligand.
Type:
Grant
Filed:
December 13, 2016
Date of Patent:
October 30, 2018
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Mark T. Bilodeau, Craig A. Dunbar, Timothy E. Barder, Edward R. Lee, Rossitza G. Alargova, Danielle N. Rockwood, Rajesh Shinde, Patrick Lim Soo, Benoît Moreau
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one carboxylate or carbamate ligand.
Type:
Grant
Filed:
December 18, 2014
Date of Patent:
July 3, 2018
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Mark T. Bilodeau, Benoît Moreau, Adam H. Brockman
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
April 10, 2018
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Mark T. Bilodeau, Benoît Moreau, Adam H. Brockman, Kristan Meetze, Kerry Whalen, Richard Wooster, Rossitza G. Alargova
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one polar moiety as a ligand.
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one carboxylate or carbamate ligand.
Type:
Grant
Filed:
December 19, 2013
Date of Patent:
January 31, 2017
Assignee:
PLACON THERAPEUTICS, INC.
Inventors:
Mark T. Bilodeau, Craig A. Dunbar, Timothy E. Barder, Edward R. Lee, Rossitza G. Alargova, Danille N. Rockwood, Rajesh Shinde, Patrick Lim Soo, Benoît Moreau
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
Type:
Grant
Filed:
November 18, 2015
Date of Patent:
August 2, 2016
Assignee:
Placon Therapeutics, Inc.
Inventors:
Mark T. Bilodeau, Benoît Moreau, Adam H. Brockman