Patents Assigned to Plant Bioscience Limited
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Patent number: 11519001Abstract: This invention relates to a plant E3 ubiquitin ligase (termed DA2) which acts synergistically with DA1 to control seed and organ size. Methods of increasing plant yield are provided that comprise reducing the expression or activity of DA2 in a plant that is deficient in DA1 expression or activity. Plants with increased yield and methods of producing such plants are also provided.Type: GrantFiled: April 17, 2019Date of Patent: December 6, 2022Assignees: INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY CHINESE ACADEMY OF SCIENCES, PLANT BIOSCIENCE LIMITEDInventors: Yunhai Li, Tian Xia, Na Li, Jack Dumenil, Michael Bevan
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Patent number: 11147825Abstract: A composition comprising glucoraphanin for use in: reducing fasting serum glucose levels in a subject administered with said composition when compared to a subject not administered said composition; and/or preventing diabetes mellitus and/or a condition associated therewith, treating diabetes mellitus and/or a condition associated therewith, or a combination thereof in a subject; wherein the composition is intermittently administered to the subject between about 1 to about 5 times per week such that said subject is administered with a weekly dose of between about 300 to about 2500 ?moles of glucoraphanin, as well as uses of a composition prepared from a high glucosinolate broccoli and/or methods of: reducing fasting serum glucose levels in a subject having elevated fasting serum glucose levels; preventing diabetes mellitus and/or a condition associated therewith in a subject; treating a subject having diabetes mellitus and/or a condition associated therewith; or combinations thereof.Type: GrantFiled: June 24, 2016Date of Patent: October 19, 2021Assignee: Plant Bioscience LimitedInventor: Richard Mithen
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Patent number: 11118188Abstract: This invention relates to the expression a DA1 protein with a mutation that disrupts or inactivates the LIM domain or the LIM-like domain within cells of a plant. This may increase the yield or enhance a yield-related trait of the plant. Methods, plants and plant cells are provide.Type: GrantFiled: May 7, 2019Date of Patent: September 14, 2021Assignee: Plant Bioscience LimitedInventors: Michael Bevan, Jack Dumenil
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Patent number: 10947549Abstract: The invention is based on an expression enhancer sequence derived from the RNA-2 genome segment of a bipartite RNA virus, in which a target initiation site in the RNA-2 genome segment has been mutated. Deletion of appropriate start codons upstream of the main RNA2 translation initiation can greatly increase in foreign protein accumulation without the need for viral replication. Also provided are methods, vectors and systems, including the ‘hyper-translatable’ Cowpea Mosaic Virus (“CPMV-HT”) based protein expression system.Type: GrantFiled: August 31, 2020Date of Patent: March 16, 2021Assignee: PLANT BIOSCIENCE LIMITEDInventors: Frank Sainsbury, George Peter Lomonossoff
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Patent number: 10822613Abstract: The invention is based on an expression enhancer sequence derived from the RNA-2 genome segment of a bipartite RNA virus, in which a target initiation site in the RNA-2 genome segment has been mutated. Deletion of appropriate start codons upstream of the main RNA2 translation initiation can greatly increase in foreign protein accumulation without the need for viral replication. Also provided are methods, vectors and systems, including the ‘hyper-translatable’ Cowpea Mosaic Virus (“CPMV-HT”) based protein expression system.Type: GrantFiled: August 11, 2017Date of Patent: November 3, 2020Assignee: PLANT BIOSCIENCE LIMITEDInventors: Frank Sainsbury, George Peter Lomonossoff
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Patent number: 10472685Abstract: The present invention relates to a method for determining the genotype of a Cruciferous vegetable plant for a plant with an increased glucosinolate level, comprising obtaining a sample of nucleic acids from said plant or a portion thereof and detecting in said nucleic acids a polymorphism at the Myb28 locus that is genetically linked to an increased glucosinolate level.Type: GrantFiled: November 22, 2016Date of Patent: November 12, 2019Assignees: SEMINIS VEGETABLE SEEDS, INC., PLANT BIOSCIENCE LIMITEDInventors: Richard F. Mithen, Maria Traka, Bart W. Brugmans
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Patent number: 10337021Abstract: This invention relates to the expression a DA1 protein with a mutation that disrupts or inactivates the LIM domain or the LIM-like domain within cells of a plant. This may increase the yield or enhance a yield-related trait of the plant. Methods, plants and plant cells are provided.Type: GrantFiled: November 5, 2014Date of Patent: July 2, 2019Assignee: Plant Bioscience LimitedInventors: Michael Bevan, Jack Dumenil
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Patent number: 10329577Abstract: This invention relates to a plant E3 ubiquitin ligase (termed DA2) which acts synergistically with DA1 to control seed and organ size. Methods of increasing plant yield are provided that comprise reducing the expression or activity of DA2 in a plant that is deficient in DA1 expression or activity. Plants with increased yield and methods of producing such plants are also provided.Type: GrantFiled: July 30, 2014Date of Patent: June 25, 2019Assignees: Institute of Genetics and Developmental Biology Chinese Academy of Sciences, Plant Bioscience LimitedInventors: Yunhai Li, Tian Xia, Na Li, Jack Dumenil, Michael Bevan
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Patent number: 9796958Abstract: We describe the production and use of an extract obtained from Musa spp., preferably from bananas, in the promotion of growth of Gram-positive bacteria such as lactic acid bacteria. The extract is also useful for growth enhancement of environmentally-stressed Gram negative bacteria. Fermented foods containing such extracts are also described.Type: GrantFiled: November 7, 2006Date of Patent: October 24, 2017Assignee: Plant Bioscience LimitedInventors: Primrose Pamela Elaine Freestone, Richard David Haigh, Mark Lyte
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Patent number: 9752136Abstract: The present invention relates to novel polypeptides derived from endolysins from a bacteriophage of Clostridium perfringens and to nucleic acid molecules encoding the same, as well as compositions thereof. The invention also provides uses of such polypeptides and nucleic acid molecules in the diagnosis and treatment of conditions and diseases associated with microbial cells such as Clostridium perfringens. In particular, the invention provides a polypeptide having endolysin activity derived from bacteriophage ?CP51 of Clostridium perfringens and uses thereof.Type: GrantFiled: August 5, 2015Date of Patent: September 5, 2017Assignee: PLANT BIOSCIENCE LIMITEDInventors: Melinda Mayer, Arjan Narbad
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Patent number: 9738900Abstract: The invention relates to transgenic plants with improved growth and nitrogen use efficiency expressing nitrate transporter gene, methods of making such plants and methods for improving growth and nitrogen use efficiency.Type: GrantFiled: October 4, 2016Date of Patent: August 22, 2017Assignees: Plant Bioscience Limited, Nanjing Agricultural UniversityInventors: Guohua Xu, Xiaorong Fan, Qirong Shen, Anthony Miller
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Patent number: 9733206Abstract: We describe a soil chemistry sensor for in-situ soil chemistry sensing, the sensor comprising a probe incorporating a first, ion-selective electrode and a second, reference electrode, wherein said ion-selective electrode comprises a first-electrode housing defining a first lumen having an ion-selective plug towards a distal end, said first-electrode including a first conductor in a first electrolyte, wherein said reference electrode comprises a second electrode housing defining a second lumen having a porous reference electrode plug towards a distal end, said second electrode including a second conductor in a second electrolyte, wherein said ion-selective plug and said porous reference electrode plug are within 10 mm of one another, and wherein said porous reference electrode plug and said ion-selective plug each comprise a polymer.Type: GrantFiled: December 20, 2013Date of Patent: August 15, 2017Assignee: Plant Bioscience LimitedInventors: Tony Miller, Pierre-Henri Le Besnerais, Hugo Malaurie
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Patent number: 9624502Abstract: This invention relates to the identification of a regulator protein (termed DA) which controls the size of plant seeds and organs in Arabidopsis and other plants. Manipulation of DA protein expression may useful, for example, in improving crop yield and increasing plant biomass.Type: GrantFiled: October 10, 2008Date of Patent: April 18, 2017Assignee: PLANT BIOSCIENCE LIMITEDInventors: Michael Bevan, Yunhai Li
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Patent number: 9567650Abstract: The present invention relates to a method for determining the genotype of a Cruciferous vegetable plant for a plant with an increased glucosinolate level, comprising obtaining a sample of nucleic acids from said plant or a portion thereof and detecting in said nucleic acids a polymorphism at the Myb28 locus that is genetically linked to an increased glucosinolate level.Type: GrantFiled: September 12, 2013Date of Patent: February 14, 2017Assignees: Seminis Vegetable Seeds, Inc., Plant Bioscience LimitedInventors: Richard F. Mithen, Maria Traka, Bart W. Brugmans
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Patent number: 9238820Abstract: A plant comprising a modified Flowering Locus (FT) polynucleotide expressing a modified polypeptide exhibits altered flowering time, floral numbers and/or increased seed production. Different mutant sequences conferring different phenotypes are disclosed.Type: GrantFiled: August 2, 2012Date of Patent: January 19, 2016Assignees: THE UNIVERSITY OF WARWICK, PLANT BIOSCIENCE LIMITEDInventors: Yiguo Hong, Steve Jackson, Chunyang Li
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Publication number: 20150323491Abstract: We describe a soil chemistry sensor for in-situ soil chemistry sensing, the sensor comprising a probe incorporating a first, ion-selective electrode and a second, reference electrode, wherein said ion-selective electrode comprises a first-electrode housing defining a first lumen having an ion-selective plug towards a distal end, said first-electrode including a first conductor in a first electrolyte, wherein said reference electrode comprises a second electrode housing defining a second lumen having a porous reference electrode plug towards a distal end, said second electrode including a second conductor in a second electrolyte, wherein said ion-selective plug and said porous reference electrode plug are within 10 mm of one another, and wherein said porous reference electrode plug and said ion-selective plug each comprise a polymer.Type: ApplicationFiled: December 20, 2013Publication date: November 12, 2015Applicant: Plant Bioscience LimitedInventors: Tony MILLER, Pierre-Henri LE BESNERAIS, Hugo MALAURIE
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Patent number: 9023811Abstract: The present invention relates to a composition comprising a high glucosinolate Cruciferous vegetable (such as a high glucosinolate broccoli) having a high level of glucosinolate and/or at least one derivative thereof for use in the treatment or prevention of a cardiovascular disease or for use in promoting heart and/or cardiovascular health.Type: GrantFiled: December 23, 2010Date of Patent: May 5, 2015Assignee: Plant Bioscience LimitedInventor: Richard Mithen
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Patent number: 9012721Abstract: The invention relates to transgenic plants with improved growth and nitrogen use efficiency expressing nitrate transporter gene, methods of making such plants and methods for improving growth and nitrogen use efficiency.Type: GrantFiled: February 4, 2014Date of Patent: April 21, 2015Assignees: Plant Bioscience Limited, Nanjing Agricultural UniversityInventors: Guohua Xu, Xiaorong Fan, Qirong Shen, Anthony Miller
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Publication number: 20140345001Abstract: The present invention relates to altering the biomass and/or structure of a plant, in order to maximise its potential as a source of feedstock or increase its potential as a feedstock for the paper industry. CLE41 and/or CLE42 are used to manipulate growth and structure of the vascular tissue of the plant. The present invention also provides plants in which the levels of CLE41 and/or CLE42 are increased compared to those of a native plant grown under identical conditions, and parts of such plants. Also provided are methods for using such plants or plant parts in the production of plant derived products such as paper or biofuels.Type: ApplicationFiled: April 15, 2014Publication date: November 20, 2014Applicant: PLANT BIOSCIENCE LIMITEDInventors: Simon Turner, Peter Etchells
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Patent number: 8871997Abstract: Disclosed are a variety of methods for achieving enhanced expression from a target nucleotide sequence in a plant e.g. comprising the step of transiently introducing into a tissue of a plant (e.g. a leaf) a first nucleic acid comprising the target nucleotide sequence and a second nucleic acid encoding a Post Transcriptional Gene Silencing (PTGS) suppressor protein (preferably of viral or plant origin), wherein the first and second nucleic acids are comprised within a single binary vector, construct, or the first and second nucleic acid sequences are comprised within a first binary vector and a second binary vector construct respectively. The plant tissue may then be harvested for the protein. Such methods can give much higher levels of gene expression than are obtainable using stable transgenes, or certain replicating vectors.Type: GrantFiled: November 20, 2006Date of Patent: October 28, 2014Assignee: Plant Bioscience LimitedInventors: David Charles Baulcombe, Olivier Voinnet, Andrew John Hamilton