Abstract: Provided are novel compounds of Formulas (I) and (II), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful as dual FKBP12/FKABP inhibitors. Also provided are pharmaceutical compositions comprising the novel compounds of Formulas (I) and (II) and their use in treating Parkinson's disease.
Type:
Grant
Filed:
June 29, 2021
Date of Patent:
July 29, 2025
Assignee:
Plex Pharmaceuticals, Inc.
Inventors:
Surya Kanta De, Sridhar G. Prasad, Marshall C. Peterman
Abstract: Provided are novel compounds of Formulas (I) and (II), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful as dual FKBP12/FKABP inhibitors. Also provided are pharmaceutical compositions comprising the novel compounds of Formulas (I) and (II) and their use in treating Parkinson's disease.
Type:
Grant
Filed:
August 21, 2018
Date of Patent:
August 20, 2024
Assignee:
PLEX PHARMACEUTICALS, INC.
Inventors:
Surya Kanta De, Sridhar G. Prasad, Marshall C. Peterman