Abstract: The current invention relates to a method of differentiation of human pluripotent stem cells into a human stem-cell derived population of cardiomyocytes. The method comprises the use of specific combination of steps and compounds to induce and/or promote differentiation. The method also comprises steps directed to further maturation of the cardiomyocytes obtained with the method of the invention. Also provided are kits for use in a method of differentiation as well as cell populations obtainable with the method disclosed.
Type:
Application
Filed:
August 31, 2016
Publication date:
September 6, 2018
Applicant:
Pluriomics B,V,
Inventors:
Stefan Robbert Braam, Ana Catarina Martins Grandela