Abstract: A monitoring system for monitoring a liquid handling system may comprise at least one liquid level sensor and/or at least one gateway computer. The at least one liquid level sensor may be configured to monitor at least one liquid level of at least one liquid handling element. The at least one gateway computer may be in communication with the at least one liquid level sensor. The at least one gateway computer may be configured to receive sensor readings, report information describing the readings, identify at least one rule-triggering event, and perform an action in response to identifying the at least one rule-triggering event in accordance with at least one rule.