Patents Assigned to PolarityTE, Inc.
  • Methods For Development And Use Of Minimally Polarized Function Cell Micro-Aggregate Units In Tissue Applications Using LGR4, LGR5, And LGR6 Expressing Epithelial Stem Cells
    Publication number: 20230181797
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Application
    Filed: February 3, 2023
    Publication date: June 15, 2023
    Applicant: POLARITYTE, INC.
    Inventor: Denver M. LOUGH
  • Methods for development and use of minimally polarized function cell micro-aggregate units in tissue applications using LGR4, LGR5 and LGR6 expressing epithelial stem cells
    Patent number: 11596714
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: March 7, 2023
    Assignee: POLARITYTE, INC.
    Inventor: Denver M. Lough
  • Methods for development and use of minimally polarized function cell micro-aggregate units in tissue applications using LGR4, LGR5 and LGR6 expressing epithelial stem cells
    Patent number: 11338060
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: May 24, 2022
    Assignee: PolarityTE, Inc
    Inventor: Denver M. Lough
  • Methods related to minimally polarized functional units
    Patent number: 11266765
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: March 8, 2022
    Assignee: PolarityTE, Inc.
    Inventor: Denver M. Lough
  • Methods related to minimally polarized functional units
    Patent number: 11000629
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: May 11, 2021
    Assignee: PolarityTE, Inc.
    Inventor: Denver Lough
  • Methods related to minimally polarized functional units
    Patent number: 10926001
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: February 23, 2021
    Assignee: PolarityTE, Inc.
    Inventor: Denver M. Lough
  • ADVANCED SPECIFIC HARVEST, CONTAINMENT, AND DEPLOYMENT SYSTEM (ASHCADS)
    Publication number: 20190059861
    Abstract: Kits and methods are provided for harvesting samples such as cells or tissue including skin tissue for use in research and therapeutic protocols. Kits and methods for deploying grafts, constructs or other products for therapeutic use are also provided. Use of the kits temporarily preserves the viability and/or function of the sample (such as a tissue sample) and/or therapeutic agent.
    Type: Application
    Filed: August 22, 2018
    Publication date: February 28, 2019
    Applicant: PolarityTE, Inc.
    Inventors: Denver Lough, Edward Swanson
  • METHODS FOR DEVELOPMENT AND USE OF MINIMALLY POLARIZED FUNCTION CELL MICRO-AGGREGATE UNITS IN TISSUE APPLICATIONS USING LGR4, LGR5 AND LGR6 EXPRESSING EPITHELIAL STEM CELLS
    Publication number: 20190046691
    Abstract: Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
    Type: Application
    Filed: October 19, 2018
    Publication date: February 14, 2019
    Applicant: PolarityTE, Inc.
    Inventor: Denver Lough
  • Package for transport and handling of biological materials
    Patent number: D894729
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: September 1, 2020
    Assignee: PolarityTE, Inc.
    Inventors: Denver Lough, Edward Swanson