Abstract: A process for the extraction and purification of alkaloids from plant material wherein the first extraction is conducted with an aqueous solution of a strong acid and the acid extract is clarified by flocculation. The alkaloid is recovered from the clarified extract in a second extraction step by means of an organic solvent, or be absorption on a cationic exchange resin or by adsorption on an adsorbing material. The alkaloid is then recovered and purified. With respect to the known processes the extraction time is reduced as well as the isomerization cases and costs and risks involved with the use of organic solvents. Most of impurities are precipitated with the flocculation thus making easier the recovery of the alkaloid.