Patents Assigned to Pollyplus Transfection
  • Cationic siRNAs, synthesis and use for RNA interference
    Patent number: 10927371
    Abstract: The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: February 23, 2021
    Assignees: Centre National De La Recherche Scientifique (CNRS), Universite De Strasbourg, Pollyplus Transfection
    Inventors: France Jean-Paul Behr, Mitsuharu Kotera, Nadege Pfender, Jean-Serge Remy