Patents Assigned to Polymer Technology Systems, Inc.
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Patent number: 10145840Abstract: A system for preserving a blood sample and removing hematocrit includes a casing, the casing having a sample port and a lateral flow strip in the casing, the lateral flow strip receiving a sample through the sample port, and flowing the sample down a length of the lateral flow strip.Type: GrantFiled: August 31, 2016Date of Patent: December 4, 2018Assignee: Polymer Technology Systems, Inc.Inventors: Aniruddha Patwardhan, Gary L. Hughes
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Patent number: 10145854Abstract: An extended range test strip includes a simple system where the end user can determine the concentration of the analyte at high concentration with a single drop of whole blood. A single drop of blood spreads across a spreading layer and into multiple reagent stacks. Multiple reagent stacks of the test strip may be configured to test for different ranges by adding a peroxide modulator. Readings from multiple reagent stacks producing a colorimetric response may be tested simultaneously. Working from the lowest range to the highest range of reagent stacks, the first reagent stack to be less than its maximum range is considered to be the reagent stack that is producing a colorimetric response related to the actual amount of analyte in the sample.Type: GrantFiled: March 10, 2014Date of Patent: December 4, 2018Assignee: Polymer Technology Systems, Inc.Inventors: Aniruddha Patwardhan, Gary L. Hughes, William Benedict
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Patent number: 10144949Abstract: A system for electrochemically detecting AST and ALT includes a first sampler for producing pyruvate from ALT and a second sampler for producing pyruvate from AST. The system further includes an electrochemical test strip for receiving processed samples from the first and second samplers, the processed samples containing pyruvate. The system further includes a meter for reading the electrochemical test strip and indicating an amount of AST and ALT in the sample.Type: GrantFiled: December 28, 2016Date of Patent: December 4, 2018Assignee: Polymer Technology Systems, Inc.Inventors: Gary L. Hughes, Aniruddha Patwardhan
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Patent number: 10054603Abstract: A system for detecting an analyte with a reagentless dry test strip includes a collector for collecting a blood sample from a user. The system additionally includes a mixer for receiving the collector and mixing the blood sample. The system additionally includes reagents, located in the mixer, for mixing with the blood sample. The system additionally includes a dry test strip for receiving the blood sample mixed with the reagents.Type: GrantFiled: September 1, 2016Date of Patent: August 21, 2018Assignee: Polymer Technology Systems, Inc.Inventor: Aniruddha Patwardhan
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Patent number: 9989542Abstract: A system for determining a level of a lipid analyte corrected for hematocrit includes a test strip configured to receive a sample and a meter configured to receive the test strip. The system further includes circuitry and a microprocessor, the circuitry and microprocessor configured to read the test strip and the sample and determine a level of a lipid analyte and correct the level of the lipid analyte based on a hematocrit level of the sample.Type: GrantFiled: November 25, 2015Date of Patent: June 5, 2018Assignee: Polymer Technology Systems, Inc.Inventors: Gary L. Hughes, Robert Huffstodt, Keith Moskowitz
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Patent number: 9933444Abstract: A system for determining a level of Cotinine and Anabasine in a sample includes a test strip configured to receive a sample; and a meter configured to receive the test strip wherein the meter is configured to read the test strip and detect a level of Anabasine and Cotinine.Type: GrantFiled: January 22, 2016Date of Patent: April 3, 2018Assignee: Polymer Technology Systems, Inc.Inventors: Keith Moskowitz, Christopher Dailey, Kristin Westerfield, Charles Xie
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Patent number: 9671401Abstract: A method of adjusting a final signal value measured on a lateral flow assay test strip, by: identifying a pre-determined calibration method for the test strip, wherein the pre-determined calibration method corresponds to the manufacturing lot from which the test strip has been made; measuring signal values while performing a lateral flow assay reaction on a test strip; determining a final signal value; and adjusting the final signal value based upon the identified pre-selected calibration method for the test strip.Type: GrantFiled: January 20, 2012Date of Patent: June 6, 2017Assignee: Polymer Technology Systems, Inc.Inventor: Benjamin R. Irvin
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Patent number: 9632080Abstract: A diagnostic multi-layer dry phase test strip with integrated biosensors for use in measuring more than one analyte in a fluid sample includes a body having a port for introducing a fluid sample. Within the body is a spreader layer configured to evenly spread the fluid sample received through the port. The test strip further includes at least one enzyme reaction layer in fluidic communication with the spreader layer. The test strip also includes a first electrode layer in fluidic communication with the at least one enzyme reaction layer. The first electrode layer includes a set of electrodes for each of the at least one enzyme reaction layer. Each set of electrodes is capable of electrically interacting with the fluid sample.Type: GrantFiled: June 11, 2009Date of Patent: April 25, 2017Assignee: Polymer Technology Systems, Inc.Inventor: Björn F. Lindemann
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Publication number: 20170056876Abstract: A pinch wall and dam system for controlling fluid flow movement between a sample receiving pad and a test strip includes a sample receiving pad and a test strip in contact with the sample receiving pad. The fluid seeps more quickly under the first portion of the pinch wall than under the second portion of the pinch wall, such that the test strip becomes saturated prior to excess fluid being absorbed in the portion of the sample receiving pad away from the test strip such that the test strip does not become flooded, the portion of the sample receiving pad positioned away from the test strip being sufficiently sized to absorb the excess fluid. The pinch wall and dam system further includes a dam, sitting on top of the sample receiving pad, the dam preventing the backflow of fluid from an area near the first portion of the pinch wall.Type: ApplicationFiled: September 2, 2016Publication date: March 2, 2017Applicant: Polymer Technology Systems, Inc.Inventors: Keith Moskowitz, Christopher Dailey, Charles Xie, Richard Lee, Bao Phan
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Publication number: 20170059596Abstract: A system for detecting an analyte with a reagentless dry test strip includes a collector for collecting a blood sample from a user. The system additionally includes a mixer for receiving the collector and mixing the blood sample. The system additionally includes reagents, located in the mixer, for mixing with the blood sample. The system additionally includes a dry test strip for receiving the blood sample mixed with the reagents.Type: ApplicationFiled: September 1, 2016Publication date: March 2, 2017Applicant: Polymer Technology Systems, Inc.Inventor: Aniruddha Patwardhan
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Publication number: 20170059551Abstract: A system for preserving a blood sample and removing hematocrit includes a casing, the casing having a sample port and a lateral flow strip in the casing, the lateral flow strip receiving a sample through the sample port, and flowing the sample down a length of the lateral flow strip.Type: ApplicationFiled: August 31, 2016Publication date: March 2, 2017Applicant: Polymer Technology Systems, Inc.Inventors: Aniruddha Patwardhan, Gary L. Hughes
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Patent number: 9470698Abstract: In one embodiment, a test strip for testing for cholesterol-related blood analytes in whole blood includes a red blood cell separation layer, the red blood cell separation layer separating red blood cells from a blood sample applied to the test strip as the blood sample flows downward through the red blood cell separation layer. The test strip further includes a reaction layer receiving the blood sample from the red blood cell separation layer, the reaction layer including POE-POP-POE block copolymer, a surfactant, and a reflectivity changing reactant, the POE-POP-POE block copolymers solubilizing essentially only non-LDL cholesterol analytes, the non-LDL cholesterol analytes reacting with the reflectivity changing reactant in order to change a reflectivity of the blood sample.Type: GrantFiled: December 7, 2015Date of Patent: October 18, 2016Assignee: Polymer Technology Systems, Inc.Inventors: Timothy Riley, Aniruddha Patwardhan, Frank LaDuca
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Patent number: 9395373Abstract: A method of determining concentrations of a plurality of analytes from a single blood sample placed in a single opening. A portion of the single blood sample is absorbed by a test matrix that includes a plurality of layers and a chromogenic agent. A colored response is generated by the test matrix. The colored response is proportional to the concentration of a first analyte. A portion of the single blood sample is drawn into a capillary tube and placed in contact with an electrode and a counter-electrode. An electrical property of the single blood sample is analyzed through the electrode and counter-electrode. The electrical property is proportional to the concentration of a second analyte in the single blood sample.Type: GrantFiled: March 15, 2013Date of Patent: July 19, 2016Assignee: Polymer Technology Systems, Inc.Inventors: Robert Huffstodt, James J. Sutor
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Patent number: 9207184Abstract: In one embodiment, a test strip for testing for cholesterol-related blood analytes in whole blood includes a red blood cell separation layer, the red blood cell separation layer separating red blood cells from a blood sample applied to the test strip as the blood sample flows downward through the red blood cell separation layer. The test strip further includes a reaction layer receiving the blood sample from the red blood cell separation layer, the reaction layer including POE-POP-POE block copolymer, a surfactant, and a reflectivity changing reactant, the POE-POP-POE block copolymers solubilizing essentially only non-LDL cholesterol analytes, the non-LDL cholesterol analytes reacting with the reflectivity changing reactant in order to change a reflectivity of the blood sample.Type: GrantFiled: May 1, 2013Date of Patent: December 8, 2015Assignee: Polymer Technology Systems, Inc.Inventors: Timothy Riley, Aniruddha Patwardhan, Frank LaDuca
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Patent number: 9180455Abstract: A blood sampler device includes a blood collector and a sampler body. The blood collector is designed to collect a sample of a fluid, such as blood, from a user and to be inserted into the sampler body, such that the collected blood can be discharged into a liquid chamber in the sampler body to mix with a liquid stored in the liquid chamber for testing. The blood collector includes vents that are designed to facilitate the flow of air out of the liquid chamber during this insertion, such that a lower and more consistent pressurization can be achieved within the liquid chamber. This design may also increase user comfort and enhance the accuracy of testing performed on the collected fluid.Type: GrantFiled: August 16, 2012Date of Patent: November 10, 2015Assignee: Polymer Technology Systems, Inc.Inventors: Bao Phan, Martin Antoine Mathelier, Hoang Quoc Chau, Simin Yao, Eugene Prais
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Patent number: 9182418Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: GrantFiled: January 31, 2014Date of Patent: November 10, 2015Assignee: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight
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Patent number: 8865089Abstract: Described here are systems, devices, cartridges, methods, and kits for detecting or quantifying at least two different analytes using at least two different techniques, in a single sample. The cartridges typically comprise at least two test sites and the location of at least one test site is not dependent on a corresponding measurement device. The systems generally comprise a device, memory, and a processing module. The device comprises a light source, an array detector, and a port configured to accept at least a portion of a cartridge. The processing module is configured to perform an image analysis of the cartridge. The methods comprise the steps of acquiring calibration information, acquiring an image of the cartridge, performing an image analysis, and cycling through specific detection or quantification techniques corresponding to the techniques required by the test sites. Computer readable media are also described.Type: GrantFiled: December 14, 2010Date of Patent: October 21, 2014Assignee: Polymer Technology Systems, Inc.Inventors: Joel M. Blatt, Carole R. Stivers
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Publication number: 20140273270Abstract: An optical lateral flow fluid analyte testing device includes a test strip having at least one zone for measuring the concentration of a target analyte in a fluid sample. Devices and methods for facilitating a reliable reading are disclosed.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: Polymer Technology Systems, Inc.Inventors: Xin (Cindy) Wang, Hoi-Cheong Steve Sun, Paul M. Ripley, Mu Wu
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Publication number: 20140255960Abstract: An extended range test strip includes a simple system where the end user can determine the concentration of the analyte at high concentration with a single drop of whole blood. A single drop of blood spreads across a spreading layer and into multiple reagent stacks. Multiple reagent stacks of the test strip may be configured to test for different ranges by adding a peroxide modulator. Readings from multiple reagent stacks producing a colorimetric response may be tested simultaneously. Working from the lowest range to the highest range of reagent stacks, the first reagent stack to be less than its maximum range is considered to be the reagent stack that is producing a colorimetric response related to the actual amount of analyte in the sample.Type: ApplicationFiled: March 10, 2014Publication date: September 11, 2014Applicant: POLYMER TECHNOLOGY SYSTEMS, INC.Inventors: Aniruddha Patwardhan, Gary L. Hughes, William Benedict
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Publication number: 20140147870Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: ApplicationFiled: January 31, 2014Publication date: May 29, 2014Applicant: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight