Patents Assigned to Polypeptide Laboratories Holding (PPL) AB
  • Method for preparation of peptides with psWang linker
    Patent number: 11236123
    Abstract: The invention discloses a method for the preparation of a peptide by liquid phase coupling of two fragments, an N-terminal fragment and a C-terminal fragment of the desired peptide, wherein the C-terminal fragment is protected on its C-terminal COOH by a psWang linker; the method is demonstrated with liraglutide wherein the C-terminal fragment carries the Palmitoyl-Glu-OtBu residue on the Lys.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: February 1, 2022
    Assignee: Polypeptide Laboratories Holding (PPL) AB
    Inventors: Luciano Forni, Daniel Carbajo Lopez, Fernando Albericio Palomera
  • Method for the preparation of H-Arg(MIS)-OH
    Patent number: 10407389
    Abstract: The invention discloses a method for the preparation of N-omega-(1,2-dimethylindole-3-sulfonyl)-L-arginine and its derivatives using L-ornithine.
    Type: Grant
    Filed: October 9, 2016
    Date of Patent: September 10, 2019
    Assignee: POLYPEPTIDE LABORATORIES HOLDING (PPL) AB
    Inventors: Deyong Tan, Joanna Dai, Matthieu Giraud, Fernando Albericio Palomera
  • Method for solid phase peptide synthesis
    Patent number: RE46830
    Abstract: A novel method for synthesizing a Hirulog peptide is devised.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: May 8, 2018
    Assignee: Polypeptide Laboratories Holding (PPL) AB
    Inventors: Anne-Sophie Droz, Jasmine Schnidrig, Nicole Studer, Stéphane Varray, Corinne Wenger, Oleg Werbitzky