Patents Assigned to POLYPID LTD.
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Patent number: 11471414Abstract: The present invention provides methods for preventing, inhibiting or treating a surgical site infection associated with a surgical operation comprising the step of applying to the surgical site a biocompatible, biodegradable substrate being impregnated and/or having its surface coated fully or partially with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the surgical site.Type: GrantFiled: February 13, 2020Date of Patent: October 18, 2022Assignee: POLYPID LTD.Inventor: Noam Emanuel
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Patent number: 10758639Abstract: The present invention relates to pharmaceutical compositions and methods for the treatment of peri-implant diseases, in particular peri-implant disease characterized by the destruction of the crest of the alveolar bone supporting the implant. Specifically, the method comprising the step of applying to a peri-implant bone displaying crestal resorption a 5 pharmaceutical composition comprising biocompatible bone augmentation material coated with a matrix composition which provides local controlled and prolonged release of at least one pharmaceutically active agent at the bone loss site.Type: GrantFiled: September 27, 2015Date of Patent: September 1, 2020Assignee: Polypid Ltd.Inventor: Noam Emanuel
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Patent number: 10682412Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: GrantFiled: September 6, 2018Date of Patent: June 16, 2020Assignee: POLYPID LTD.Inventor: Noam Emanuel
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Patent number: 10463617Abstract: The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: GrantFiled: February 17, 2015Date of Patent: November 5, 2019Assignee: PolyPid Ltd.Inventor: Noam Emanuel
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Patent number: 10105443Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: GrantFiled: August 23, 2016Date of Patent: October 23, 2018Assignee: POLYPID LTD.Inventor: Noam Emanuel
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Patent number: 9616032Abstract: There are provided compositions for extended release of a nucleic acid agent, comprising a lipid-saturated matrix formed with a biodegradable polymer. Also provided are methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.Type: GrantFiled: August 4, 2014Date of Patent: April 11, 2017Assignee: Polypid Ltd.Inventors: Noam Emanuel, Yosef Rosenfeld
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Patent number: 9421271Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: GrantFiled: October 26, 2014Date of Patent: August 23, 2016Assignee: POLYPID LTD.Inventor: Noam Emanuel
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Patent number: 9173976Abstract: The present invention relates to compositions, methods and medical devices for the treatment of bone voids and bone defects. The methods of the invention comprise the step of applying to a bone void or bone defect site a composition comprising a matrix which provides local prolonged release of at least one antibiotic agent at the bone void site.Type: GrantFiled: August 1, 2013Date of Patent: November 3, 2015Assignee: Polypid Ltd.Inventor: Noam Emanuel
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Patent number: 8992979Abstract: The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: GrantFiled: July 14, 2010Date of Patent: March 31, 2015Assignee: Polypid Ltd.Inventors: Noam Emanuel, Moshe Neuman, Shlomo Barak
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Patent number: 8877242Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: GrantFiled: July 14, 2009Date of Patent: November 4, 2014Assignee: Polypid Ltd.Inventors: Noam Emanuel, Moshe Neuman, Shlomo Barak
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Patent number: 8795726Abstract: The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.Type: GrantFiled: January 18, 2011Date of Patent: August 5, 2014Assignee: Polypid Ltd.Inventors: Noam Emanuel, Yosef Rosenfeld
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Publication number: 20120294944Abstract: The present invention provides compositions for extended release of a nucleic acid agent, a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of the nucleic acid agent.Type: ApplicationFiled: January 18, 2011Publication date: November 22, 2012Applicant: POLYPID LTD.Inventors: Noam Emanuel, Yosef Rosenfeld
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Publication number: 20120114756Abstract: The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: ApplicationFiled: July 14, 2010Publication date: May 10, 2012Applicant: POLYPID LTD.Inventors: Noam Emanuel, Moshe Neuman, Shlomo Barak
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Publication number: 20110117197Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.Type: ApplicationFiled: July 14, 2009Publication date: May 19, 2011Applicant: POLYPID LTD.Inventors: Noam Emanuel, Moshe Neuman, Shlomo Barak