Abstract: A front-load syringe injector system includes a front-load injector apparatus having mounted on a front face thereof a detachably engageable adapter. A driving head is engaged with a drive mechanism of the injector and the driving head disengageably engages a plunger mounted in an angiographic syringe mounted on the adapter. At least one of the plunger and driving head and syringe elements interacts with the adapter to effect engagement and disengagement of the plunger and driving head and syringe with respect to one another.