Abstract: A transdermal administrating device is provided which includes an active electrode having a conductive electrode layer and a conductive drug layer applied on the bottom surface of the conductive electrode layer. The bottom surface of the conductive drug layer is capable of being placed in contact with skin. The device also includes an inert electrode capable of being placed in contact with skin and spaced from the active electrode, a set of conductive electrode layers each having a different standard single electrode potential, and a controller for measuring an internal resistance of the skin tissue under the region between the conductive electrode layers and for controlling an electric current passing between the active electrode and the inert electrode based on the variation in the internal resistance. In addition, a dermocontact mechanism is provided for keeping the active electrode, the inert electrode, and the set of conductive electrode layers in contact with skin.

Abstract: A compound for use especially as an antiviral drug, mainly containing salts of heteropolyanions consisting of a tungstoantimonate (III) vanadium-mixed metal oxide or related salts represented by formula [(XW9O33)2V3O3]P−, where p is a positive number between 9 and 12 and X is Sb, P. As or Bi and especially Sb. An antiviral drug having a broad spectrum of antiviral activity, high potent efficacy and low toxicity is provided.

Abstract: The present invention provides a transdermal administrating device capable of improving the quality of life of patients comprising an active electrode 2 having a conductive electrode layer 2a and a conductive drug layer 2b applied on the bottom surface of the conductive electrode layer, the bottom surface of the conductive drug layer 2b being capable of being placed in contact with skin 1, an inert electrode 4 capable of being placed in contact with skin and spaced from the active electrode 2, a set of conductive electrode layers 3, 3′, each having a different standard single lectrode potential, a controller for measuring an internal resistance Rd of the skin tissue 1 under the region between the conductive electrode layers 3, 3′ and controlling an electric current passing between the active electrode 2 and the inert electrode 4 based on the variation in the internal resistance Rd, and a dermocontact means 8 for keeping the active electrode 2, the inert electrode 4, the set of conductive electrode

Abstract: The device for the preparation of fibrous material to be tested comprises means for fastening said fibrous material, means for partitioning the fibrous material, and means for clamping and separating the fibrous material. The means for fastening, the means for partitioning and the means for clamping operate in essentially parallel surface planes. Since the device essentially operates by performing linear translations in surface planes, it is suited to automation, simple, maintenance-friendly and inexpensive.

Abstract: A first conductive sheet film is disposed on a partial area of the skin-contact surface of an adhesive member. A conductive matrix is disposed on the first conductive film, the conductive matrix being dispersed with a drug to be permeated through skin. A second conductive film is disposed on the conductive matrix, the second conductive film having a plurality of openings distributed on the surface of the conductive matrix and having a standard single electrode potential lower than that of the first conductive film. An insulating film is disposed between the conductive matrix and the second conductive film in a manner such that an electric short path is not formed between the conductive matrix and the second conductive film. The insulating film has a plurality of openings distributed on the surface of the conductive matrix, and a connection member electrically interconnects the first and second conductive films.

Abstract: A skin-contact type medical treatment apparatus has a first conductive member having a contact surface made of single metal or alloy and a second conductive member having a contact surface made of semiconductor. The standard single-electrode potential of the semiconductor constituting the contact surface of the second conductive member is lower than a standard single-electrode potential of the metal constituting the contact surface of the first conductive member. The apparatus further includes a parallel circuit of a diode and a capacitor electrically connected to the first and second conductive members. The apparatus is used by making both the contact surfaces of the first and second conductive members in contact with skin.

Abstract: A skin-contact type therapeutic apparatus has a pair of electrodes which are put in contact with skin at different areas at the same time and a voltage pulse train generator circuit connected to the pair of electrodes. The voltage pulse generator circuit generates a unipolar voltage pulse train having a pulse width of 100 .mu.s to 10 ms, a duty ratio of 50% or smaller, a frequency of 20 to 800 Hz, and a peak voltage of 0.05 to 20 V. By pressing the pair of electrodes against skin and applying such a unipolar voltage pulse train, it is possible to treat the skin to resolve allergic dermatitides and/or enhance metabolism by suppressing allergic reactions, and to regenerate skin in a short time without using medicine.

Abstract: A skin-contact type medical treatment apparatus is provided which includes: a first conductive member having a first skin-contact surface in contact with a first surface of skin when in use, the first skin-contact surface being made of metal or its alloy; and a second conductive member having a second skin-contact surface in contact with a second surface of skin different from the first surface when in use together with the first conductive member, the second skin-contact surface being made of n-type semiconductor material having a standard single electrode potential lower than that of the first skin-contact surface. The first and second conductive members are electrically connected by a protective resistor at an area different from the first and second skin-contact surfaces, the protective resistor having a resistance value in the range of from 0.1 to 50 M.OMEGA..