Patents Assigned to Pono Corporation
  • CONJUGATED ANTI-MICROBIAL COMPOUNDS AND CONJUGATED ANTI-CANCER COMPOUNDS AND USES THEREOF
    Publication number: 20150150995
    Abstract: Disclosed herein are synthesis methods for generation of conjugated anti-microbial compounds and conjugated anti-cancer compounds. Several embodiments, related to the uses of such compounds in the treatment of infections, in particular those caused by drug-resistant bacteria. Some embodiments relate to targeting cancer based on the metabolic signature of tumor cells.
    Type: Application
    Filed: August 9, 2013
    Publication date: June 4, 2015
    Applicant: PONO CORPORATION
    Inventors: Karl Milton Taft, III, Jarred Roy Engelking
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CONDITIONS RESPONSIVE TO PROTEASOME INHIBITION
    Publication number: 20140187526
    Abstract: The invention disclosed herein generally relates to methods and compositions for inhibiting proteasome activity comprising a syrbactin compound having the structure of Formula I or II:
    Type: Application
    Filed: December 2, 2013
    Publication date: July 3, 2014
    Applicant: Pono Corporation
    Inventors: Andre S. Bachmann, Robert Dudler, Michael Groll
  • Pharmaceutical compositions for the treatment of conditions responsive to proteasome inhibition
    Patent number: 8597904
    Abstract: The invention disclosed herein generally relates to methods and compositions for inhibiting proteasome activity comprising a syrbactin compound have the structure of Formula (I) or (II).
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: December 3, 2013
    Assignee: Pono Corporation
    Inventors: Andre S. Bachmann, Robert Dudler, Michael Groll