Patents Assigned to Pontifica Universidad Catolica De Chile
  • Patent number: 10851559
    Abstract: The invention relates to a combination of a foundation anchor and energy damper for vertical tanks or similar containers for liquids with a thin wall and continuous support, comprising an energy dissipation component centrally connected to a foundation anchor component by means of a linking component, the energy dissipation component comprising one or more superimposed and horizontally arranged energy dissipating plates with a rhombic shape truncated at the vertices thereof, wherein the shorter diagonal is normal to the wall of the tank and the side ends or vertices corresponding to the longer diagonal have quadrangular extensions for support on a load transmission component that is connected to the wall of the tank so as to transmit and distribute the forces developed by the one or more energy dissipating plates. Alternatively, the energy dissipating plates are trapezoidal with the longer parallel side tangential to the wall of the tank.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: December 1, 2020
    Assignee: PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE
    Inventors: José Luis Almazán Campillay, Nathaly Karina Valdebenito Tapia, Nicolás Felipe Tapia Flores
  • Patent number: 9511120
    Abstract: The present invention is related to the use of the angiotensin-(1-9) peptide or peptides derived therefrom, which are biological or chemical analogs, for preparing medicaments useful for preventing, reverting, inhibiting and/or reducing hypertension and/or inducing vasodilation. Furthermore, this invention also comprises a vector overexpressing the homologous angiotensin-II converting enzyme (ACE2) for elevating the concentration in the blood and/or tissues of the angiotensin-(1-9) peptide. This vector may be adenovirus, retrovirus, lentivirus or adeno-associated virus containing the gene encoding for ACE2.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: December 6, 2016
    Assignees: PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE, UNIVERSIDAD DE CHILE
    Inventors: Maria Paz Ocaranza Jeraldino, Jorge Emilio Jalil Milad, Sergio Alejandro Lavandero González, Mario Martin Chiong Lay, Luis Fernando Michea Acevedo
  • Patent number: 9345710
    Abstract: Compounds and combinations of them that inhibit phosphatidic phosphohydrolase (PAP) enzymatic activity are formulated into pharmaceuticals useful in cancer treatment. Inhibitors of PAP can be used for blocking the progression of cancers that depend on the epidermal growth factor receptor (EGFR), its oncogenic variants and other members of its ErbB tyrosine kinase receptor family, through induction of their endocytosis, thus making them inaccessible to the extracellular stimuli that promote maintenance and progression of cancer.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: May 24, 2016
    Assignee: PONTIFICA UNIVERSIDAD CATOLICA DE CHILE
    Inventors: Alfonso Gonzalez, Andrea Soza, Claudia Metz
  • Publication number: 20150190472
    Abstract: The present invention is related to the use of the angiotensin-(1-9) peptide or peptides derived therefrom, which are biological or chemical analogues, for preparing medicaments useful for preventing, reverting, inhibiting and/or reducing hypertension and/or inducing vasodilation. Furthermore, this invention also comprises a vector overexpressing the homologous angiotensin-II converting enzyme (ACE2) for elevating the concentration in the blood and/or tissues of the angiotensin-(1-9) peptide. This vector may be adenovirus, retrovirus, lentivirus or adeno-associated virus containing the gene encoding for ACE2.
    Type: Application
    Filed: April 5, 2012
    Publication date: July 9, 2015
    Applicants: Pontifica Universidad Catolica De Chile, Universidad De Chile
    Inventors: María Paz Ocaranza Jeraldino, Jorge Emilio Jalil Milad, Sergio Alejandro Lavandero González, Mario Martín Chiong Lay, Luis Fernando Michea Acevedo
  • Patent number: 9044375
    Abstract: A device that stimulates bone tissue formation capable of generating vibrations with different frequency components at the same time and that can be applied locally to different parts of the patient's body, wherein such device comprises a vibration generator capable of generating vibrations with different frequencies and variable fastener to attach to different parts of the body.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: June 2, 2015
    Assignee: PONTIFICA UNIVERSIDAD CATOLICA DE CHILE
    Inventors: Maria Loreto Reyes General, Micah Etan Ortuzar Dworsky, Rodrigo Eduardo Carmi Lahsen
  • Publication number: 20110301514
    Abstract: A device that stimulates bone tissue formation capable of generating vibrations with different frequency components at the same time and that can be applied locally to different parts of the patient's body, wherein such device comprises different frequency vibration generating means and variable fastening means to attach to different parts of the body.
    Type: Application
    Filed: October 27, 2009
    Publication date: December 8, 2011
    Applicant: Pontifica Universidad Catolica De Chile
    Inventors: Maria Loreto Reyes General, Micah Etan Ortuzar Dworsky, Rodrigo Eduardo Carmi Lahsen