Abstract: A composition and method of using same is disclosed for the permanent sterilization of female subjects without the need for expensive surgery or highly skilled personnel. The composition comprises a gel-forming carrier substance which sets-up on introduction into the fallopian tubes and holds in place a tissue fibrosing promoting material carried thereby for a period of time to cause fibrous tissue growth which closes the fallopian tubes and results in sterilization.

Abstract: A material dispensing apparatus for placing a material in the uterine cavity and moving the material from the uterine cavity into the fallopian tubes of a female. An elongated probe carries an expandable member, and a housing connected to the probe has a piston and cylinder structure and a container for storing the material. Material and expansion drive mechanisms are connected to a single actuator selectively controllable by an operator. When the actuator is operated it is moved into the housing to both dispense the material and expand the expandable member. Pressure control means are provided in the drive linkage for expanding the expandable member to assure that a predetermined maximum pressure is not surpassed. The operator may fully depress the actuator and the pressure control means will both determine the maximum pressure and substantially maintain that pressure should a leak occur.