Abstract: New compounds of formula I are described
The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders, where a reduction in the O-methylation of catecholamines may be of therapeutical benefit, such as Parkinson's disease and parkinsonian disorders, gastrointestinal disturbances, edema formation states and hypertension.
Type:
Grant
Filed:
December 17, 1999
Date of Patent:
January 28, 2003
Assignee:
Portela & C.A., S.A.
Inventors:
Jan Benes, Patricio Manuel Viera Araujo Soares Da Silva, David Alexander Learmonth