Abstract: There is provided an oxygenation assembly submersible within a body of water. The oxygenation assembly includes a mass transfer vessel configured to receive water and promote dissolving of oxygen therewithin at least in part using pressure from the body of water. The vessel is elongate and may have a fixed diameter. The oxygenation assembly includes a bubble generator downstream of the vessel and which functions as a throttling device. The bubble generator is configured to dissipate pressure within the vessel in a manner that promotes breaking up of remaining undissolved gaseous bubbles. The oxygenation assembly may include an aeration system coupled to and in this example in line with the vessel. The aeration system disperses water of elevated dissolved oxygen content throughout a larger volume of water having a lower bulk dissolved oxygen concentration.

Abstract: In certain embodiments, an ocean wave energy extraction system including a wave energy panel may capture kinetic energy from an ocean wave as a force applied to a flexible membrane that drives the WEP back and forth in a reciprocating motion. The WEP dimensions may be selected so that the energy extracted from the wave is maximized and the added mass is minimized. A flexible membrane may be supported on two opposite edges by structural members that may pivot about a base. The shape of the flexible membrane may reciprocate in response to alternating horizontal wave orbital velocities. The force applied to the flexible membrane may be transmitted through the structural members to a power extraction device, such as a hydraulic pump or an electrical generator, that may be mounted to the base. Multiple WEPs may be arranged parallel to the wave crest to produce additional power.

Abstract: Disclosed are compounds of formula (I): and pharmaceutically acceptable salts thereof. The compounds of the invention are BDII-selective inhibitors of BET proteins, and have therapeutic potential for treating cancer, acute kidney disease, and viral infections, among other diseases.

Abstract: In certain embodiments, an ocean wave energy extraction system including a wave energy panel may capture kinetic energy from an ocean wave as a force applied to a flexible membrane that drives the WEP back and forth in a reciprocating motion. The WEP dimensions may be selected so that the energy extracted from the wave is maximized and the added mass is minimized. A flexible membrane may be supported on two opposite edges by structural members that may pivot about a base. The shape of the flexible membrane may reciprocate in response to alternating horizontal wave orbital velocities. The force applied to the flexible membrane may be transmitted through the structural members to a power extraction device, such as a hydraulic pump or an electrical generator, that may be mounted to the base. Multiple WEPs may be arranged parallel to the wave crest to produce additional power.

Abstract: In certain embodiments, an ocean wave energy extraction system including a wave energy panel may capture kinetic energy from an ocean wave as a force applied to a flexible membrane that drives the WEP back and forth in a reciprocating motion. The WEP dimensions may be selected so that the energy extracted from the wave is maximized and the added mass is minimized. A flexible membrane may be supported on two opposite edges by structural members that may pivot about a base. The shape of the flexible membrane may reciprocate in response to alternating horizontal wave orbital velocities. The force applied to the flexible membrane may be transmitted through the structural members to a power extraction device, such as a hydraulic pump or an electrical generator, that may be mounted to the base. Multiple WEPs may be arranged parallel to the wave crest to produce additional power.

Abstract: A plumbing distribution and control panel system is provided. The plumbing distribution and control panel system has a main control panel unit having an interior. A portion of each of a plurality of pipes of a residence or commercial building may pass through the control panel to various zones of the building such as, for example, a water heater or tankless heater, a kitchen, a bathroom, a utility room, a laundry room, a basement, an exterior unit, or a mechanical room of a commercial building. The main control panel may allow a user to control the flow of water through the pipes in those zones. The main control panel allows for the easy cut-off of flowing water which may prevent damage to the residence or commercial building. A wireless system may also allow a user to wirelessly control the flow of water through the pipes.

Abstract: A sensor for measuring multiple properties of a fluid, such as oil, including level, temperature, water contamination, and dielectric where the sensing elements include two or more interdigitated electrodes, a capacitive relative humidity sensor, and a temperature sensing element.

Abstract: An isokinetic control module and method for incorporation on both new and existing exercise equipment. The control module replaces standard friction and hydraulic resistance components offering constant speed of the moveable elements of the machine rather than a selected resistance or weight. The constant user-generated resistance prevents injury and enhances strength training of the targeted muscle groups by maintaining constant strain on those muscles throughout the exercise. This method and device incorporates both a PCFC valve and a check valve device, removing all resistance the moment the user stops applying force to the machine. This enhances safety and facilitates the rapid return of the lifting element to its home position between repetitions. An optional graphical display is also disclosed.

Abstract: A method of preparing bilirubin IX? from biliverdin IX? diester, the method including: 1) adding sodium hydroxide dissolved in a first methanol solution to biliverdin IX? diester dissolved in a second methanol solution, to yield a first mixture; adding water to the first mixture to hydrolyze biliverdin IX? diester; adding an acid to the first mixture to adjust the pH value thereof; removing a first solvent of the first mixture through rotary evaporation, and removing an inorganic salt through rinsing, and vacuum drying, to yield biliverdin IX?; and 2) dissolving the biliverdin IX? in an alcoholic solution, and adding a radical scavenger and borohydride to the alcoholic solution, to yield a second mixture; adding a ketone to the second mixture to decompose excess borohydride; adding the acid to the second mixture to adjust the pH value thereof; and removing a second solvent of the second mixture through rotary evaporation.

Abstract: A system and method employing wear debris sensors to monitor the operation of a lubricated mechanical system such as a gearbox (e.g., in a wind turbine), a transmission or an engine in order to control operation of the gearbox in order to reduce damage and/or extend the useful life of the gearbox.

Abstract: A method and system for estimating the remaining useful life of a filter in a lubrication system is disclosed along with exemplary system components.

Abstract: A segment for a modular floatation collar comprises a frame having a recessed compartment and a removable decking covering the recessed compartment. The frame is mounted on a floatation unit. There are a plurality of rigging hardpoints and a plurality of installation hardpoints disposed along the frame. A universal connection at each end of the frame allows the segment to be connected to an adjacent segment either linearly along a common axis or orthogonally at a right angle. The floatation unit extends between adjacent segments in the floatation collar.

Abstract: A sensor for measuring multiple properties of a fluid, such as oil, including level, temperature, water contamination, and dielectric where the sensing elements include two or more interdigitated electrodes, a capacitive relative humidity sensor, and a temperature sensing element.

Abstract: A system and method employing wear debris sensors to monitor the operation of a lubricated mechanical system such as a gearbox (e.g., in a wind turbine), a transmission or an engine in order to control operation of the gearbox in order to reduce damage and/or extend the useful life of the gearbox.

Abstract: A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis has a radially expansible support and a bifurcation traversing portion. The radially expansible support is configured to be deployed in at least a portion of the branch body lumen. The bifurcation traversing portion has a biostable portion having a first end and a second end. The first end is located adjacent to the radially expansible support. The bifurcation traversing portion also has a biodegradable portion having a first end coupled with the second end of the biostable portion. The biodegradable portion has a second end disposed at an end of the prosthesis opposite the radially expansible support. When deployed, the bifurcation traversing portion extends from the radially expansible support across a bifurcation and into a main body lumen such that the carina is supported thereby.

Abstract: A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis comprises a radially expansible support, at least two axially elongate longitudinal members, at least one of which can be fronds, extending from an end of the support, and a circumferential member connected to at least one axially elongate longitudinal member and unconnected to at least one other axially elongate longitudinal member.

Abstract: A vibration damper device comprising: a rigid bracket having a substantially flat side shoulder including a substantially rectilinear longitudinal groove or slit thereon, and which is anchorable in a rigid manner on the body of the lintel or of the pillar, next to the covering beam or the plug panel, to arrange said side shoulder facing the lateral side of the covering beam or the surface of the plug panel, with the longitudinal groove or slit locally substantially parallel to the longitudinal axis of the covering beam or to the longitudinal axis of the plug panel; a movable slider slidably engages the longitudinal groove or slit, and is anchorable in a rigid manner to the body of the covering beam or to the body of the plug panel; and a deformable connecting member with elastoplastic behavior, which is connectable to the movable slider in a rigid manner to the bracket.

Abstract: A method for operating an oxygen sensor arrangement senses the oxygen in a breathing loop of a breathing apparatus. The sensor arrangement includes a primary oxygen sensor to measure the oxygen in the breathing loop, a secondary oxygen sensor to measure the oxygen in the breathing loop, and a control arrangement to obtain measures from the oxygen sensor. A test channel arrangement provides a first gas having a first fraction of oxygen from a first gas supply to the primary oxygen sensor at a position adjacent to the primary oxygen sensor. A test valve arrangement opens and closes the flow of the first gas through the test channel arrangement. The control arrangement actuates the first test valve arrangement to provide an amount of the first gas to the primary oxygen sensor via the test channel arrangement and obtain measures from the primary and secondary oxygen sensors.

Abstract: An oxygen sensor arrangement is arranged to sense the oxygen in a breathing loop of a breathing apparatus. The sensor arrangement comprises at least one primary oxygen sensor arranged to operatively measure the oxygen in the breathing loop, and a control arrangement for obtaining measures from the oxygen sensor. A test channel arrangement is adapted to operatively provide a first gas having a first fraction of oxygen from a first supply to the primary oxygen sensor at a position adjacent to or directly adjacent to the primary oxygen sensor. A first test valve arrangement is arranged to operatively open and close the flow of the first gas through the test channel arrangement. The control arrangement is arranged to operatively actuate the first test valve arrangement so as to provide an amount of the first gas to the primary oxygen sensor via the test channel arrangement.