Patents Assigned to Postech Academy Industry
  • Method of Regulating Mammalian Target-of-Rapamycin Activity by Interaction Between Phospholipase D and RHEB
    Publication number: 20090304667
    Abstract: The present invention relates to method of regulating mammalian target-of-rapamycin (mTOR) based on a novel finding of a regulating mechanism of mTOR by a phospholipase D (PLD), and Ras homolog enriched in brain (Rheb). Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibitin mTOR.
    Type: Application
    Filed: August 3, 2007
    Publication date: December 10, 2009
    Applicant: Postech Academy Industry
    Inventors: Sung-Ho Ryu, Pann-Ghill Suh, Sang-Hoon Ha, Mi-Nam Lee, Hyun-Ju Lee, II-Shin Kim, Do-Hyung Kim, Tae-Hoon Lee