Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
October 22, 2019
Date of Patent:
February 28, 2023
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Daniel Hicklin, William Winston, Cynthia S. Dugan, Nels P. Nielson
Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
March 30, 2018
Date of Patent:
September 27, 2022
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Nels P. Nielson, Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Heather Brodkin, Jose-Andres Salmeron-Garcia, Christopher James Nirschl, Philipp Steiner
Abstract: Provided herein are antibodies, or antigen binding fragments thereof, that selectively bind to NRP-1 and its isoforms and homologs, and compositions comprising the antibodies, or antigen binding fragments thereof. Also provided are methods of using the antibodies, or antigen binding fragments thereof, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
January 3, 2019
Date of Patent:
November 30, 2021
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Jose-Andres Salmeron-Garcia, Nels P. Nielson, Heather Brodkin
Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to GITR and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
February 20, 2018
Date of Patent:
April 27, 2021
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Jose-Andres Salmeron-Garcia, Heather Brodkin, Sonja Kleffel, Nels P. Nielson
Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
June 19, 2017
Date of Patent:
December 17, 2019
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Daniel Hicklin, William Winston, Cynthia Seidel-Dugan, Nels P. Nielson
Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to NRP-1 and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
February 20, 2018
Date of Patent:
March 12, 2019
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Jose-Andres Salmeron-Garcia, Nels P. Nielson, Heather Brodkin
Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
Type:
Grant
Filed:
February 13, 2017
Date of Patent:
July 25, 2017
Assignee:
Potenza Therapeutics, Inc.
Inventors:
Daniel Hicklin, William Winston, Cynthia S. Dugan, Nels P. Nielson