Abstract: Pharmaceutical compositions of the invention comprise functionalized lactam derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity, wherein A is selected from a group consisting of:
Type:
Grant
Filed:
May 10, 2019
Date of Patent:
February 24, 2026
Assignees:
Temple University-Of The Commonwealth System of Higher Education, Praeventix, LLC
Inventors:
Daniel J. Canney, Benjamin E. Blass, Kevin M. Blattner, Douglas A. Pippin
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
Type:
Grant
Filed:
March 31, 2022
Date of Patent:
June 24, 2025
Assignees:
Temple University-Of The Commonwealth System of Higher Education, Praeventix, LLC
Inventors:
Daniel J. Canney, Benjamin E. Blass, Kevin M. Blattner, Douglas A. Pippin
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
Type:
Grant
Filed:
September 9, 2020
Date of Patent:
May 3, 2022
Assignees:
Temple University—Of The Commonwealth System of Higher Education, Praeventix, LLC
Inventors:
Daniel J. Canney, Benjamin E. Blass, Kevin M. Blattner, Douglas A. Pippin
Abstract: Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
Type:
Grant
Filed:
November 15, 2017
Date of Patent:
December 8, 2020
Assignees:
TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, PRAEVENTIX, LLC
Inventors:
Daniel J. Canney, Benjamin E. Blass, Kevin M. Blattner, Douglas A. Pippin