Patents Assigned to Prana Biotechnology Limited
  • Publication number: 20210230159
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Application
    Filed: April 7, 2021
    Publication date: July 29, 2021
    Applicant: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • Patent number: 11008319
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: May 18, 2021
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • Publication number: 20200317670
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Application
    Filed: June 24, 2020
    Publication date: October 8, 2020
    Applicant: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • Patent number: 10738050
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: August 11, 2020
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • Patent number: 10287285
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: May 14, 2019
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • Patent number: 9302993
    Abstract: The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: April 5, 2016
    Assignee: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Gaik Beng Kok, Guy Krippner
  • Publication number: 20150359796
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD).
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • Publication number: 20150335635
    Abstract: The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 26, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Kevin Jeffrey BARNHAM, Elisabeth Colette Louise GAUTIER, Gaik Beng KOK, Guy KRIPPNER
  • Patent number: 9169211
    Abstract: The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: October 27, 2015
    Assignee: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Gaik Beng Kok, Guy Krippner
  • Patent number: 9145375
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: September 29, 2015
    Assignee: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • Publication number: 20150094334
    Abstract: The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 2, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Kevin Jeffrey BARNHAM, Elisabeth Colette Louise GAUTIER, Gaik Beng KOK, Guy KRIPPNER
  • Patent number: 8975278
    Abstract: The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: March 10, 2015
    Assignee: Prana Biotechnology Limited
    Inventors: Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Gaik Beng Kok, Guy Krippner
  • Publication number: 20150025072
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane HUGGINS, Jack Gordon PARSONS
  • Publication number: 20150025108
    Abstract: The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.
    Type: Application
    Filed: October 9, 2014
    Publication date: January 22, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Kevin Jeffrey BARNHAM, Elisabeth Colette Louise GAUTIER, Gaik Beng KOK, Guy KRIPPNER
  • Patent number: 8889695
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: November 18, 2014
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • Publication number: 20140088122
    Abstract: The present invention relates generally to the field of treatment and prophylaxis of retinal degenerative diseases. More particularly, the present invention contemplates a method for preventing, reducing the risk of development of, or otherwise treating or ameliorating the symptoms of, age-related macular degeneration (AMD) or related retinal conditions in mammals and in particular humans. The present invention further provides therapeutic compositions enabling dose-dependent or dose-specific administration of agents useful in the treatment and prophylaxis of age-related macular degeneration or related retinal degenerative conditions.
    Type: Application
    Filed: November 22, 2013
    Publication date: March 27, 2014
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane HUGGINS, Gaik Being KOK
  • Patent number: 8318171
    Abstract: This invention relates to methods and compositions for the treatment or alleviation of Alzheimer's disease and of other conditions related to abnormal protein aggregation. In particular, the invention relates to methods and compositions for the immunotherapy of Alzheimer's disease, Parkinson's disease, and cataract. In one aspect the invention provides a method of prophylaxis, treatment or alleviation of a condition characterized by pathological aggregation and accumulation of a specific protein associated with an immunizing-effective dose of one or more tyrosine cross-linked compounds, and optionally also comprising copper ions complexed to the compound. Alternatively passive immunization against a tyrosine cross-linked compound may be used. Prophylactic or therapeutic compositions and diagnostic methods are also disclosed and claimed.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: November 27, 2012
    Assignees: Prana Biotechnology Limited, The General Hospital Corporation
    Inventors: Ashley Bush, Robert Cherny
  • Patent number: 8163760
    Abstract: The present invention relates generally to therapeutic agents, formulations comprising them and their use in the treatment, amelioration and/or prophylaxis of glioma brain tumors and related conditions. The therapeutic agent comprises two fused 6-membered rings with at least a nitrogen at position 1 and a hydroxyl at position 8.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: April 24, 2012
    Assignee: Prana Biotechnology Limited
    Inventors: Ashley Bush, Penelope Jane Huggins, Jack Gordon Parsons, Gaik Beng Kok, Vijaya Kenche
  • Publication number: 20120040980
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Application
    Filed: December 23, 2009
    Publication date: February 16, 2012
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • Publication number: 20110071167
    Abstract: The present invention relates generally to the field of treatment and prophylaxis of retinal degenerative diseases. More particularly, the present invention contemplates a method for preventing, reducing the risk of development of, or otherwise treating or ameliorating the symptoms of, age-related macular degeneration (AMD) or related retinal conditions in mammals and in particular humans. The present invention further provides therapeutic compositions enabling dose-dependent or dose-specific administration of agents useful in the treatment and prophylaxis of age-related macular degeneration or related retinal degenerative conditions.
    Type: Application
    Filed: November 23, 2010
    Publication date: March 24, 2011
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Ashley BUSH, Colin Louis MASTERS, Penelope Jane HUGGINS, Jack Gordon PARSONS, Gaik Beng KOK, Vijaya KENCHE, Mariana EL SOUS