Patents Assigned to Precision BioSciencens, Inc.
  • SELF-LIMITING VIRAL VECTORS ENCODING NUCLEASES
    Publication number: 20230193318
    Abstract: Disclosed herein are viral vectors for use in recombinant molecular biology techniques. In particular, the present disclosure relates to self-limiting viral vectors comprising genes encoding site-specific endonucleases as well as recognition sequences for site-specific endonucleases such that expression of the endonuclease in a cell cleaves the viral vector and limits its persistence time. In some embodiments, the viral vectors disclosed herein also carry directives to delete, insert, or change a target sequence.
    Type: Application
    Filed: November 22, 2022
    Publication date: June 22, 2023
    Applicant: Precision BioSciencens, Inc.
    Inventors: Derek Jantz, James Jefferson Smith, Michael G. Nicholson