Abstract: In comparison with the treatment using only a single vessel, this invention can more efficiently and more completely facilitate the temperature of liquid to be kept at a predetermined temperature by transferring liquid from a liquid storage vessel to a vessel maintained at a predetermined temperature. In comparison with the case using only a single vessel, in which control of raising and lowering the temperature needs be executed by a heating means or transferring a container accompanied by liquid to a heating position, the reaction can more efficiently be executed by this aspect of the invention, and the amplification can be executed more easily and in a shorter time. And as the mechanism for transferring the container needs not be mounted, the structure of the equipment can be simplified. Furthermore, all the process including the control of temperature, can be executed with one continuous operation by this aspect of the invention.

Abstract: The present invention relates to a method and apparatus for controlling magnetic particles by a sample distributor and is intended to process a sample liquid with high precision, sensitivity and reliability by arresting magnetic particles to separate them from the liquid and by suspending the magnetic particles in a liquid to mix the magnetic particles with the liquid again. The pipette portion of this invention has a front end portion, a reservoir portion, a liquid passage connecting the front end portion and the reservoir portion, and a separation region in the liquid passage that is subjected to a magnetic field. The pipette portion of this construction draws in or discharges a liquid for processing.

Abstract: Technological preposition of the present invention is a liquid processing method making use of a pipette device which sucks a liquid containing a target high molecular substance from inside of a vessel through a chip detachably set on a sucking port or a discharging port of a liquid sucking/discharging line and transfers this liquid or target high molecular substance to the next target processing position for the purpose to execute such works as quantifying, separating, taking out, pipetting, clarifying condensing, and diluting a liquid or a target high molecular substance contained in a liquid and also such works as extracting, recovering, and isolating the target high molecular substance by means of sucking and discharging a liquid with a pipette device and controls by a magnetic body over magnetic particles and/or a filter combined according to the necessity, and the chip can isolate the target high molecular substance by having the substance attracted onto magnetic particles or with a filter set on each c

Abstract: The present invention relates to a carrier holding micro-substances, system suspending such carriers, apparatus for manipulating such carriers and method of controlling the position of such carriers. The object of the present invention is to execute assays for various target substances and so on efficiently, at low cost, easily, and reliably.

Abstract: A multiple vessel container for testing fluids comprises a gap part formed to have a width smaller than the caliber of a front end portion of a liquid sucking/discharging line. The gap part has a shape capable of aspirating and discharging all liquid through the front end portion of the line, even when the front end portion is in contact with the inside bottom of the container. The container is formed such that, upon fluid discharging, reaction between a sample and a reagent can be made uniform by discharging and diffusing aspirated liquid.

Abstract: A magnetic material attracting/releasing control method makes use of a pipette device sucking a liquid from or discharging a liquid into a container. A magnet body or bodies are provided in a liquid suction line of the pipette device, and any magnetic material contained in liquid sucked into the liquid suction line by magnetic force are deposited on the internal surface of the line. The magnetic material is released and discharged together with liquid from the liquid suction line to a state where the effect of the magnetic force generated by the magnet body is cut off.

Abstract: A magnetic material attracting/releasing control method makes use of a pipette device sucking a liquid from or discharging a liquid into a container. A magnet body or bodies are provided in a liquid suction line of the pipette device, and any magnetic material contained in liquid sucked into the liquid suction line by magnetic force are deposited on the internal surface of the line. The magnetic material is released and discharged together with liquid from the liquid suction line to a state where the effect of the magnetic force generated by the magnet body is cut off.

Abstract: A multiple vessel container for testing fluids comprises a gap part formed to have a width smaller than the caliber of a front end portion of a liquid sucking/discharging line. The gap part has a shape capable of aspirating and discharging all liquid through the front end portion of the line, even when the front end portion is in contact with the inside bottom of the container. The container is formed such that, upon fluid discharging, reaction between a sample and a reagent can be made uniform by discharging and diffusing aspirated liquid.

Abstract: A magnetic material attracting/releasing control method makes use of a pipette device sucking a liquid from or discharging a liquid into a container. A magnet body or bodies are provided in a liquid suction line of the pipette device, and any magnetic material contained in liquid sucked into the liquid suction line by magnetic force are deposited on the internal surface of the line. The magnetic material is released and discharged together with liquid from the liquid suction line to a state where the effect of the magnetic force generated by the magnet body is cut off.

Abstract: This invention provides a measuring apparatus that allows measurements of light in various inspections based on different light generating principles to be performed by a single measuring apparatus and thus widens the range of reagents that can be used, increasing the versatility of this single measuring apparatus and significantly enhancing its usefulness for users and reagent manufacturers. The measuring apparatus of this invention comprises: a light receiving unit and/or a light receiving unit holder connected to a light measuring device; a nozzle holder holding a nozzle for injecting reagents including luminescent reagents into a container; and a container containing a specimen and/or a container holder; wherein the container or container holder and the light receiving unit or light receiving unit holder, and/or the nozzle holder are coupled together to form an enclosed space shielded from external light.

Abstract: Method and apparatus are described for purifying and separating biopolymers from a homogenized biological milieu using a pipette tip. The biopolymers are complexed with first magnetic particles. A magnet is applied to the pipette tip to attract the biopolymer/magnetic particle complex to the inner surface of the pipette tip adjacent to the magnet for separation from the biological milieu. The magnet is removed and the magnetic particles dissociated and removed from the biopolymers. Second magnetic particles are bound to the biopolymers. The magnet is replaced against the exterior surface of the pipette tip, thereby attracting the bound biopolymers to the inner surface of the pipette tip adjacent to the magnet to allow separation from impurities. The biopolymers are then labeled for detection, which may include detecting the concentration and identity of the biopolymer.

Abstract: In the present invention, a disposable tip or a tip of a cleaning system is attached to a lower edge section of a nozzle, and the nozzle detects a liquid level by receiving fluctuation of a light close to the disposable tip or to an opening section at a lower end of the tip in the cleaning system, for instance, a light reflected from the liquid surface. In the present invention, not only the liquid level is detected, but also a liquid is filled in the disposable tip or the tip of a cleaning system detachably attached to the nozzle, a light is passed through the liquid in the disposable tip or the tip of a cleaning system, and a change of a light amount of the sucked liquid is detected, so that, for instance, a suction rate of the liquid, transparency thereof, contaminated by bubbles therein, clogging and a state wherein water has been exhausted are determined.

Abstract: A magnetic material attracting/releasing control method makes use of a pipette device sucking a liquid from or discharging a liquid into a container. A magnet body or bodies are provided in a liquid suction line of the pipette device, and any magnetic material contained in liquid sucked into the liquid suction line by magnetic force are deposited on the internal surface of the line. The magnetic material is released and discharged together with liquid from the liquid suction line to a state where the effect of the magnetic force generated by the magnet body is cut off.

Abstract: In the present invention, a disposable tip or a tip of a cleaning system is attached to a lower edge section of a nozzle, and the nozzle detects a liquid level by receiving fluctuation of a light close to the disposable tip or to an opening section at a lower end of the tip in the cleaning system, for instance, a light reflected from the liquid surface. In the present invention, not only the liquid level is detected, but also a liquid is filled in the disposable tip or the tip of a cleaning system detachably attached to the nozzle, a light is passed through the liquid in the disposable tip or the tip of a cleaning system, and a change of a light amount of the sucked liquid is detected, so that, for instance, a suction rate of the liquid, transparency thereof, contaminated by bubbles therein, clogging and a state wherein water has been exhausted are determined.

Abstract: The present invention is a liquid processing method making use of a pipette device which sucks a liquid containing a target high molecular substance from inside of a vessel through a chip detachably set on a sucking port or a discharging port of a liquid sucking/discharging line and transfers this liquid or target high molecular substance to the next target processing position for the purpose to execute such works as quantifying, separating, taking out, pipetting, clarifying, condensing, and diluting a liquid or a target high molecular substance contained in a liquid and also such works as extracting, recovering, and isolating the target high molecular substance by means of sucking and discharging a liquid with a pipette device and controls by a magnetic body over magnetic particles and/or a filter combined according to the necessity, and the chip can isolate the target high molecular substance by having the substance attracted onto magnetic particles or with a filter set on each chip.

Abstract: A magnetic material attracting/releasing control method makes use of a pipette device sucking a liquid from or discharging a liquid into a container. A magnet body or bodies are provided in a liquid suction line of the pipette device, and any magnetic material contained in liquid sucked into the liquid suction line by magnetic force are deposited on the internal surface of the line. The magnetic material is released and discharged together with liquid from the liquid suction line to a state where the effect of the magnetic force generated by the magnet body is cut off.

Abstract: A light-emission measuring apparatus which is capable of eliminating various secondary problems in addition to shutting off strong light from the external and preventing crosstalk. The light-emission measuring apparatus is equipped with a box-type carrier 9 having an open top surface and made to accommodate a microplate 7 comprising a plurality of wells. The box-type carrier is disposed to be movable horizontally. A light-obstruction plate having a light-receiving hole 11 is disposed above the box-type carrier to be movable vertically. The light-obstruction plate 5 is brought into tight contact with a circumference of the box-type carrier 9 to establish a black box when being moved downwardly. Further, the light-receiving hole 11 of the light-obstruction plate 5 has a cylindrical projecting bottom surface 12 so that its bottom surface side outer circumference comes into tight contact with a circumference 13 of an opening of a well top surface of the microplate 7.