Patents Assigned to Premier Research Labs, LP
  • Patent number: 9944960
    Abstract: A process for production and extraction of dihydrolipoic acid (DHLA) relates to the biotransformation of R-lipoic acid to dihydrolipoic acid. The process ferments the lipoic acid with bacteria selected from the genus of any of the following bacteria: Lactobacillus, Enterococcus, Pediococcus, or Bacillus. More particularly the present invention relates to a method for the extraction of DHLA utilizing a non-traditional solvent system, namely a food oil. Generally the DHLA that is produced in the present method is isolated from cells which have been inactivated or killed.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: April 17, 2018
    Assignee: Premier Research Labs, LP
    Inventors: Robert J. Marshall, Nickolas Labinsky, Lindsey Dunham, Michael Ratkovich, Walter Trikosko
  • Publication number: 20170137852
    Abstract: A process for production and extraction of dihydrolipoic acid (DHLA) relates to the biotransformation of R-lipoic acid to dihydrolipoic acid. The process ferments the lipoic acid with bacteria selected from the genus of any of the following bacteria: Lactobacillus, Enterococcus, Pediococcus, or Bacillus. More particularly the present invention relates to a method for the extraction of DHLA utilizing a non-traditional solvent system, namely a food oil. Generally the DHLA that is produced in the present method is isolated from cells which have been inactivated or killed.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 18, 2017
    Applicant: PREMIER RESEARCH LABS, LP
    Inventors: Robert J. Marshall, Nickolas Labinsky, Lindsey Dunham, Michael Ratkovich, Walter Trikosko
  • Publication number: 20140011244
    Abstract: A method for producing naturally derived beneficial compounds including dispersing a microbiological culture media including at least one live probiotic organism, and at least one nutraceutical and/or at least one nutritive agent in distilled water to form a broth, incubating the broth at a predetermined temperature for a select period of time to induce probiotic activity; halting the probiotic activity, and separating the desired compound from the broth.
    Type: Application
    Filed: September 9, 2013
    Publication date: January 9, 2014
    Applicant: Premier Research Labs, LP
    Inventor: Robert J. Marshall
  • Patent number: 8530209
    Abstract: A method for producing naturally derived beneficial compounds including dispersing a microbiological culture media including at least one live probiotic organism, and at least one nutraceutical and/or at least one nutritive agent in distilled water to form a broth, incubating the broth at a predetermined temperature for a select period of time to induce probiotic activity; halting the probiotic activity, and separating the desired compound from the broth.
    Type: Grant
    Filed: January 3, 2005
    Date of Patent: September 10, 2013
    Assignee: Premier Research Labs, LP
    Inventor: Robert J. Marshall
  • Patent number: 8304217
    Abstract: A stabilized dihydrolipoic acid (DHLA) compound is provided. The stabilized DHLA is derived from a microbiological culture media including at least one live probiotic organism, R-lipoic acid and at least one nutritive agent. The stabilized DHLA may be prepared by dispersing the microbiological media in distilled water to form a broth, incubating the broth at a predetermined temperature for a select period of time to induce probiotic activity, adding organic ethanol to the broth to halt the probiotic activity, and separating the derived stabilized DHLA from the broth.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: November 6, 2012
    Assignee: Premier Research Labs, LP
    Inventor: Robert J. Marshall