Patents Assigned to Prescient Neuropharma Inc.
  • 2-aminoindane analogs
    Patent number: 7034055
    Abstract: The present invention relates to therapeutically active 2-aminoindane analogs of formula (I): Also provided is a method of preparing compounds of formula (I), and pharmaceutical compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: April 25, 2006
    Assignee: Prescient Neuropharma Inc.
    Inventor: Kenneth Curry
  • Cubane derivatives as metabotropic glutamate receptor agonists or antagonists and process for their preparation
    Patent number: 6784202
    Abstract: The present invention relates to therapeutically active cubane compounds, a method of preparing the same, and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: August 31, 2004
    Assignee: Prescient NeuroPharma Inc.
    Inventors: Hassan Pajouhesh, Kenneth Curry
  • Cubane derivatives as metabotropic glutamate receptor antagonists and process for their preparation
    Publication number: 20040147482
    Abstract: Thee present invention relates to therapeutically active cubane compounds, a method of preparing the same, and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in creating diseases of the central nervous system related to the metabotropic glutamate receptor system.
    Type: Application
    Filed: January 14, 2004
    Publication date: July 29, 2004
    Applicant: Prescient NeuroPharma Inc.
    Inventors: Hassan Pajouhesh, Kenneth Curry
  • Aminoindanes
    Patent number: 6699909
    Abstract: The present invention relates to therapeutically active novel aminoindanes of formula (I). Also provided is a method of preparing compounds of formula (I), and pharmaceutical compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: March 2, 2004
    Assignee: Prescient NeuroPharma Inc.
    Inventor: Kenneth Curry
  • Methods for producing and preparing cells for cell therapy
    Patent number: 6465248
    Abstract: The invention features methods for expansion and packaging of cells. Expansion is achieved by providing cells that include neural progenitor cells; plating the cells in culture vessels at an average density of 1×105 to 7×105 cells/cm2; and culturing said cells in culture medium and under conditions permissible for proliferation of said neural progenitor cells, wherein the volume of medium results in an initial cell density of between 5×104 and 1.5×105 cells per milliliter of medium. Preparation of cells for transplantation includes providing a cell suspension that includes single cells, aggregates of fewer than two hundred cells, or a combination thereof; and re-aggregating the cells in said cell suspension, wherein greater than 50% of reaggregates consist of between 25 and 500 cells/reaggregate.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: October 15, 2002
    Assignee: Prescient NeuroPharma, Inc.
    Inventor: John Commissiong