Abstract: Disclosed is a polypeptide termed UBCE2A that catalyzes the covalent attachment of ubiquitin to the transcription factor E2A, thereby triggering the degradation of E2A. Also disclosed are DNAs encoding UBCE2A.
Type:
Application
Filed:
February 16, 2001
Publication date:
September 12, 2002
Applicant:
President and Fellows of Harvard College, a Massachusetts corporation
Inventors:
Choon-Joo Kho, Mu-En Lee, Edgar Haber, Carol Haber