Abstract: A novel process for removing endotoxin from biological fluids such as parenteral fluids and for removing or reducing the level of endotoxin from the blood of animals is disclosed. The novel process includes the utilization of certain non-ionogenic hydrophobic synthetic plastic polymers that have been found to be capable of adsorbing endotoxin from the biological fluids when placed in intimate contact therewith.

Abstract: A novel process for removing endotoxin from biological fluids such as parenteral fluids and for removing or reducing the level of endotoxin from the blood of animals is disclosed. The novel process includes the utilization of certain non-ionogenic hydrophobic synthetic plastic polymers that have been found to be capable of adsorbing endotoxin from the biological fluids when placed in intimate contact therewith.

Abstract: An in vitro process for detecting the presence of endotoxin in a biological fluid such as a parenteral fluid, whole blood, and the like, wherein amebocyte lysate from the hemolymph of the horseshoe crab, Limulus polyphemus, is intimately contacted with and incubated in the presence of a synthetic plastic polymer capable of adsorbing endotoxin which has previously been contacted with the biological fluid. The presence or absence of a gelation reaction in the amebocyte lysate is then observed. The presence of a gelation reaction determines the presence of endotoxin in the biological fluid.