Abstract: A pharmaceutical composition for Positron Emission Tomography (PET) and Boron Neutron Capture Therapy (BNCT) and the use for treating cancer thereof are provided, wherein the pharmaceutical composition comprises a compound having structure of formula I, wherein R1 is a specific peptide, one of R2, R3, and R4 is Fluorine-18 (18F) or Fluorine-19 (19F), one of the other two position is —B(OH)2, and the remaining position is hydrogen (H); a method for preparing a compound having structure of formula I is also provided in the present invention.
Abstract: A noninvasive detection method for cancer metastases is provided, which are based on the feature of the radiopharmaceutical that binds specifically to cells of cancer hepatic metastasis, so that cancer metastases can be detected by detecting the signal of the radiopharmaceutical in various organs in the subject. A specific treating method for cancer metastases by using the radiopharmaceutical as an important tool for precise treatment is also provided.
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