Patents Assigned to Primus Pharmaceuticals, Inc.
  • Patent number: 11844777
    Abstract: Methods of treating autoimmune microvascular conditions using diosmin or diosmetin are described, particularly the treatment of digital ulcers in systemic sclerosis.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: December 19, 2023
    Assignee: Primus Pharmaceuticals, Inc.
    Inventor: Robert M Levy
  • Patent number: 11278517
    Abstract: Methods of treating autoimmune microvascular conditions using diosmin or diosmetin are described, particularly the treatment of digital ulcers in systemic sclerosis.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: March 22, 2022
    Assignee: Primus Pharmaceuticals, Inc.
    Inventor: Robert M Levy
  • Publication number: 20210386758
    Abstract: The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.
    Type: Application
    Filed: January 7, 2021
    Publication date: December 16, 2021
    Applicant: Primus Pharmaceuticals, Inc.
    Inventors: Udhumansha UBAIDULLA, Sateesh KANDAVILLI, Ajay Sunil VAIRALE, Jeffrey A. WAYNE, Vijendra NALAMOTHU, Mistry MEGHAL, Refika Isil PAKUNLU
  • Patent number: 11179465
    Abstract: Topical compositions comprising a corticosteroid, at least one alcohol, and a penetration enhancing agent.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: November 23, 2021
    Assignee: Primus Pharmaceuticals, Inc.
    Inventors: Sateesh Kandavilli, Madhusudhan Bommagani, Vijendra Nalamothu, Franklin Okumu
  • Patent number: 10391114
    Abstract: Provided is a formulation and a method associated therewith for treating inflammation. The formulation includes therapeutically effective amounts of curcuminoids and two flavonoids. The two flavonoids include baicalin and catechin.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: August 27, 2019
    Assignee: Primus Pharmaceuticals, Inc.
    Inventors: Domenica Altavilla, Robert Levy
  • Patent number: 10300040
    Abstract: Provided is a pharmaceutical formulation and a method associated therewith for treating inflammation. The pharmaceutical formulation includes therapeutically effective amounts of sesquiterpenes such as ?-caryophyllene and two flavonoids. The two flavonoids include baicalin and catechin.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: May 28, 2019
    Assignee: Primus Pharmaceuticals, Inc.
    Inventor: Masayoshi Yamaguchi
  • Patent number: 10039740
    Abstract: Provided is a pharmaceutical formulation and a method associated therewith for treating inflammation. The pharmaceutical formulation includes therapeutically effective amounts of sesquiterpenes such as ?-caryophyllene and two flavonoids. The two flavonoids include baicalin and catechin.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: August 7, 2018
    Assignee: Primus Pharmaceuticals, Inc.
    Inventor: Masayoshi Yamaguchi
  • Publication number: 20170112802
    Abstract: Provided is a pharmaceutical formulation and a method associated therewith for treating inflammation. The pharmaceutical formulation includes therapeutically effective amounts of sesquiterpenes such as ?-caryophyllene and two flavonoids. The two flavonoids include baicalin and catechin.
    Type: Application
    Filed: October 14, 2016
    Publication date: April 27, 2017
    Applicant: Primus Pharmaceuticals, Inc.
    Inventor: Masayoshi Yamaguchi
  • Patent number: 9486438
    Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: November 8, 2016
    Assignee: Primus Pharmaceuticals, Inc.
    Inventor: Francesco Squadrito
  • Publication number: 20150190365
    Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.
    Type: Application
    Filed: March 18, 2015
    Publication date: July 9, 2015
    Applicant: PRIMUS PHARMACEUTICALS INC.
    Inventor: Francesco Squadrito
  • Patent number: 9066921
    Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: June 30, 2015
    Assignee: Primus Pharmaceuticals Inc.
    Inventor: Francesco Squadrito
  • Publication number: 20130210753
    Abstract: The invention relates to methods of treating Duchenne muscular dystrophy with flavonoids. The methods may include (a) providing a pharmaceutical composition comprising a therapeutically effective amount of flavonoid, and (b) administering the composition to a human patient, wherein the flavonoid comprises an isoflav-4-one with at least one of the carbons located at positions 8, 7, 6, 5, 2, 2?, 3?, 4?, 5?, or 6? modified by an alcohol group. Alternatively, the flavonoid may comprise (1) a flavan-3-ol with at least one of the carbons located at positions 8, 7, 6, 5, 4, 2?, 3?, 4?, 5?, or 6? modified by an alcohol group, or (2) a Free-B-Ring flavone with at least one of the carbons located at positions 8, 7, 6, 5 or 3 modified by an alcohol group and with at least one of the carbons located at positions 8, 7, 6, 5 or 3 modified by a glycoside group.
    Type: Application
    Filed: June 1, 2012
    Publication date: August 15, 2013
    Applicant: PRIMUS PHARMACEUTICALS INC.
    Inventors: Francesco Squadrito, Alessandra Bitto, Giuseppe Vita, Sonia Messina, Bruce P. Burnett
  • Publication number: 20130078318
    Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.
    Type: Application
    Filed: November 26, 2012
    Publication date: March 28, 2013
    Applicant: Primus Pharmaceuticals Inc.
    Inventors: Bruce P. Burnett, James D. Weir, Francesco Squadrito
  • Patent number: 8338393
    Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: December 25, 2012
    Assignee: Primus Pharmaceuticals, Inc.
    Inventors: Bruce P. Burnett, James D. Weir, Francesco Squadrito
  • Publication number: 20100190733
    Abstract: The invention relates to methods of treating Duchenne muscular dystrophy with flavonoids. The methods may include (a) providing a pharmaceutical composition comprising a therapeutically effective amount of flavonoid, and (b) administering the composition to a human patient, wherein the flavonoid comprises an isoflav-4-one with at least one of the carbons located at positions 8, 7, 6, 5, 2, 2?, 3?, 4?, 5?, or 6? modified by an alcohol group. Alternatively, the flavonoid may comprise (1) a flavan-3-ol with at least one of the carbons located at positions 8, 7, 6, 5, 4, 2?, 3?, 4?, 5?, or 6? modified by an alcohol group, or (2) a Free-B-Ring flavone with at least one of the carbons located at positions 8, 7, 6, 5 or 3 modified by an alcohol group and with at least one of the carbons located at positions 8, 7, 6, 5 or 3 modified by a glycoside group.
    Type: Application
    Filed: January 26, 2010
    Publication date: July 29, 2010
    Applicant: Primus Pharmaceuticals, Inc.
    Inventors: Francesco Squadrito, Alessandra Bitto, Giuseppe Vita, Sonia Messina, Bruce P. Burnett
  • Publication number: 20090258845
    Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.
    Type: Application
    Filed: March 23, 2009
    Publication date: October 15, 2009
    Applicant: Primus Pharmaceuticals, Inc.
    Inventors: Bruce P. Burnett, J. D. Weir, Francesco Squadrito