Abstract: The present invention provides a novel antibody fragment based antifungal conjugate selectively targeting Candida spp. comprising of at least one antimicrobial peptide at one end of the conjugate, more particularly, human Histatin-5; an antibody fragment at the other end of the conjugate, specific against Candida spp. enolase, a virulence factor protease and biofilm specific antigen of Candida spp.; at least one signal protease cleavage sequence susceptible to cleavage by virulent protease secreted by Candida spp., secreted aspartyl proteinase-1 (SAP1); and at least one flexible polypeptide linker. The signal protease cleavage sequence and the flexible polypeptide linker are in tandem with each other and placed in between the antimicrobial peptide and the antibody. The in vitro MIC-99 of the conjugate against Candida spp., is in the range of 0.2-0.3 ?M, more specifically, 0.25 ?M or 250 nM.

Abstract: A measurement system for an electrical machine includes a position sensor device arranged on a rotor of the electrical machine, a carrier connected to the position sensor device, and a temperature sensor device fastened to the carrier. The position sensor device is configured to ascertain an item of information about an orientation of the rotor. The temperature sensor is configured to ascertain a temperature of a stator of the electrical machine.

Abstract: The present invention provides a robust and effective solution to an entity or an organization by allowing to visualize the flow of automotive data signals from a source system to a sink system with different metric signals at each step and creating a mechanism for creating automotive signal quality marker (ASQM) for high quality automotive data signals by determining high value data parameters, inter-parameter correlation, data quality variation with trip duration, and frequency of data collection/distribution across datasets. The quality criterion thus developed is applied to data generated from a plurality of data sources. The ASQM may be calculated by converting the developed automotive data signals quality criterion into a numeric value on a specified scale. It can be used by all stakeholders in the value chain for consistent measurement of automotive data signals quality.

Abstract: A graphical user interface for electronic games is disclosed. The interface comprises a current weapon panel configured to display a first weapon in an active state, and a plurality of spare weapon panels configured to display weapons in the inactive state. The plurality of spare weapon panels is arranged in accordance with the panel ranking values assigned to each spare weapon panel. The selection of any one of the spare weapon panels results in a corresponding weapon in the inactive state, which is displayed on the selected spare weapon panel, being switched to the active state and promoted to the current weapon panel, and the first weapon being switched to the inactive state and relegated to a spare weapon panel. The weapons in the inactive state are dynamically ordered and displayed on the plurality of spare weapon panels according to the panel ranking value of the spare weapon panels and the predicted weapon ranking value.

Abstract: A system and method for real-time operational predictive scoring of components and services of an information technology system (ITS) for forecasting and assessing performance of the components of the ITS are provided. A data pipeline is configured to collect and store, in real-time, multiple time series signals corresponding to health, performance, and functionality of each of the components of the ITS. An operational predictive score (OPS) engine of a scoring module calculates an OPS for each of the time series signals. An OPS roll-up module of the scoring module calculates an OPS for each of the components and services in the ITS by aggregating the OPS for the individual time series signals. An alerting engine to notify operational issues and provide root cause analysis using OPS score decomposition. A visualization layer for OPS based analytics.

Abstract: The present invention relates to a pharmaceutical formulations and compositions comprising cholinergic agonist agents such as pilocarpine-R-(+)-lipoate or its salt, solvate, or hydrate thereof for oral administration with improved compliance, safety, and bioavailability. It further discloses methods of preparing the formulations and its use for the treatment of xerostomia, dry mouth and Sjogren's syndrome.

Abstract: The improved system and method disclosed herein includes training an auto-labelling engine in a plurality of iterations until a performance of the auto-labelling engine is satisfactory. The auto-labelling engine is trained based on a combination of a plurality of manually annotated first media and a plurality of second media without annotation. The method further includes receiving at least one media for labelling and using the trained auto-labeling engine to draw at least one bounding box around at least one object in the received at least one media for labelling the at least one object in the at least one media.

Abstract: A system and method for network control and optimization may be integrated into an application executed by a computing device so that the application and/or the user of the application can control the digital data network by which the application may access remote data. In one embodiment, the digital data network may include a cellular digital data network and a WiFi network.

Abstract: Disclosed is a composition for selective enrichment of progressively motile non-fragmented/intact DNA sperms during swim-up of semen sample comprising combination of electrolytes, a mix of excipients, polyyvinylpyrrolidone, recombinant human serum albumin or bovine serum albumin. A method of selective enrichment of DNA-intact sperms using the compositions of the present invention is also disclosed. The DNA fragmentation index of the swim-up sperms are less than the DNA fragmentation index of the neat samples. The media compositions of the present invention are applicable for enrichment of non-fragmented/intact DNA sperms for therapeutic purposes in the field of assisted reproductive technologies.

Abstract: Embodiments of the present disclosure relate to method and a system for managing a decentralized access to a resource. A user of a client device having a third-party application installed therein request to join the mesh network based on invite received from the owner of the IoT gateway. The mesh network comprises one or more IoT gateway. One gateway is identified based on the topology of the client device, and an optimal connection between the client device and the identified gateway is determined. The third-party application may send a resource access request for accessing a resource of the mesh network and access the requested resource through the optimal connection route thus determined. Thus, the disclosure enables a peer-to-peer mesh network infrastructure that allows secure access to the resource by a third-party application without using a cloud server to route the resource access request from the client device to the gateway.

Abstract: Our Names in physical and real world have transformed into ‘username’s in virtual digital world. Anything that we need to access in digital world asks us for a ‘username’, which can be user selected (like an e-mail address) or provided to a user (like an employee ID/Number). This ‘username’ has indeed become a SuperName, giving access to restricted areas, based on privileges, links to other services as well. So, to a cybercriminal, if a ‘username; is known, more than half the job is done. And once corresponding password is cracked, the whole digital identity lies threadbare. Damages done through transactions of such unauthorized access may get quantified, but dent to privacy is far more damaging.

Abstract: Systems and processes are provided for joint video production in an electronic device including receiving a first video stream from a first video capture device, determining an availability of a first decoder, coupling the first video stream to the first decoder in response to the first decoder being available, receiving a second video stream from a second video capture device, determining the availability of the first decoder, coupling the second video stream to a network interface for decoding by an external decoder in response to the first decoder decoding the first video stream, receiving a first decoded video stream from the first decoder, receiving a second decoded video stream from the network interface, and displaying the first decoded video stream and the second decoded video stream on a user interface.

Abstract: The present disclosure discloses a method and a system for providing a code cover to Orthogonal Frequency Division Multiplexing (OFDM) symbols in a multiple user system. A data sequence is received from each of a plurality of users. Further, a reference sequence is generated for the data sequence of each of the plurality of users. Each of the reference sequence is multiplied with a code cover which are orthogonal to each other. Each of the reference sequence is time-multiplexed with corresponding data sequence, to generate a corresponding multiplexed sequence. Further, a Discrete Fourier Transform (DFT) is performed on each of the multiplexed sequence to generate a corresponding DFT-spread-Orthogonal Frequency Division Multiplexing (DFT-s-OFDM) symbol. Lastly, the corresponding DFT-s-OFDM symbol is processed for transmitting over corresponding one or more channels.

Abstract: A highway detection system may include a telematics device associated with a vehicle having one or more sensors arranged therein, a mobile device associated with a user traveling in the vehicle, and a server computer. The server computer may receive traveling data for a trip of the user from the one or more sensors and via the telematics device. The server computer may then determine whether the user is traveling within a city or on a highway based on analysis of the traveling data for the trip of the user, which may include a statistical analysis to calculate standard deviations of metrics in the traveling data. In response to the determination, the server computer may generate a notification to transmit to the user based on whether the user is traveling within a city or on a highway and transmit the notification to the mobile device associated with the user.

Abstract: Disclosed is an electrolytic water treatment system (100) with an automated cathode cleaning mechanism thereof and in a method therefor. The electrolytic water treatment system (100) effectively removes scale forming minerals for large cooling towers and consumes less space. The electrolytic water treatment system (100) utilizes a shell in shell type arrangement so that both sides of anodes (18) and cathodes (16) are used for electrolysis simultaneously which makes the electrolytic water treatment system (100) highly efficient, effective and less expensive. By using the electrolytic water treatment system (100), the life of the anode (18) is increased at least two to three times compared to the polarity reversing method.

Abstract: Methods, systems, and apparatuses are described to implement voice search in media content for requesting media content of a video clip of a scene contained in the media content streamed to the client device; for capturing the voice request for the media content of the video clip to display at the client device wherein the streamed media content is a selected video streamed from a video source; for applying a NLP solution to convert the voice request to text for matching to a set of one or more words contained in at least close caption text of the selected video; for associating matched words to close caption text with a start index and an end index of the video clip contained in the selected video; and for streaming the video clip to the client device based on the start index and the end index associated with matched closed caption text.

Abstract: A method for video processing using Cross-Component Adaptive Loop Filter (CCALF) is provided. The method includes filtering decoded video content using a CCALF, wherein the CCALF is a 24-tap 9×9 filter.