Patents Assigned to PriZm, LLC
  • Methods for treating allan-herndon-dudley syndrome
    Patent number: 12390432
    Abstract: The present subject matter is directed to methods of treating Allan-Herndon-Dudley syndrome comprising administering 3,5-diiodothyropropionic acid (DITPA) to a subject in need thereof, wherein the DITPA administration reduces triiodothyronine (“T3”) serum levels to normal, increases T3 brain levels to normal, and maintains normal serum levels of thyroxine (T4) and thyroid stimulating hormone (TSH). The subject may be a child or an adult.
    Type: Grant
    Filed: July 11, 2023
    Date of Patent: August 19, 2025
    Assignees: PriZm, LLC, The University of Miami, The University of Chicago
    Inventors: Samuel Refetoff, Roy Weiss, Khemraj Hirani