Patents Assigned to Pro.Bio.Sint SRL
  • Process for the preparation of a deoxyuridine derivative
    Publication number: 20020128467
    Abstract: A process for the preparation of 5′-deoxy-5-fluorouridine, which comprises, the transformation of, 2′,3′-O-isopropylidene-5-fluorouridine in the corresponding 5′-O-sulfonyl derivative subsequent reaction with alkaline or earth-alkaline iodides and after hydrolysis of the isopropylidene group, reduction of the 5′-deoxy-5′-iodo-5 -fluorouridine thus obtained, is described.
    Type: Application
    Filed: April 19, 2002
    Publication date: September 12, 2002
    Applicant: Pro.Bio.Sint SRL
    Inventors: Giovanni Cotticelli, Giuseppe De Meglio, Simone Monciardini, Giancarlo Ordanini