Patents Assigned to ProCorde GmbH
  • Inhibitors of caspase-3-mediated cleavage of essential ventricular myosin light chain
    Publication number: 20050233405
    Abstract: The invention discloses use of peptide containing an essential ventricular myosin light chain type 1 (vMLC1) amino acid sequence, which is functional as cleavage site for caspase-3, in the screening for a compound for the treatment of chronic or acute cardiovascular disease. Further, screening methods for inhibitors of the caspase-3-mediated cleavage of vMLC1 are disclosed.
    Type: Application
    Filed: April 2, 2003
    Publication date: October 20, 2005
    Applicant: ProCorde GmbH
    Inventors: Alessandra Moretti, Hans-Peter Holthoff, Martin Ungerer, Gotz Munch, Karl-Ludwig Laugwitz