Abstract: The present invention relates to 4-aryl triazoles having the formula: wherein R1 is independently selected from the group consisting of: lower alkyl, lower alkenyl, lower alkynyl, lower heteroalkyl, lower heteroalkenyl, lower heteroalkynyl, heterocycloalkyl, heteroaryl, halo, CN, OR4, SR4, S(O)R4, S(O)2R4, and NR4R5; and Q is has the general formula: said compounds are useful in treating diseases associated with unwanted cytokine activity, inter alia, interleukin-1 (IL-1) and tumor necrosis factor (TNF) from cells.

Abstract: The present invention provides an absorbent structure to be used in an absorbent article such as a diaper, a training pant, an adult incontinence absorbent article, a bed mat, or the like, and the respective absorbent article. The absorbent structure of the present invention is able to rapidly acquire urine even against gravity as is quantified by the liquid drip off test defined herein.

Abstract: An improved process for providing an individually customized fresh brewed coffee beverage on demand by a consumer, in a wide range of variety and strength. Said brewing process for making relatively large quantities of fresh brewed coffee beverages (in particular customized as to desired variety, body, character and/or strengths) as chosen by multiple individual consumers just prior to their consumption, with the system being easy to use by the consumer or other individual (i.e., restaurant wait staff) obtaining the customized beverage. Further, maintenance of the equipment requires only a small amount of personal attention by the owner/operator of the equipment. “Delayed dilution” of a concentrated extract to provide a beverage brewing system which immediately (upon customer selection) provides selective dilution (based on individual consumer's selections) of a fresh brewed coffee extract after the extract has been allowed to brew and held as an extract before dilution.

Abstract: A method for making a bulky web. A web is fed in a first direction. The web is subjected to incremental stretching in a direction perpendicular to the first direction to provide a bulky web. The bulky web is then stabilized to provide a stabilized bulked web, Optionally, the bulky web may be gathered after it has been subjected to incremental stretching.

Abstract: A method of making a flangeless seam for a disposable article including the following steps: A first member of the disposable article is provided. An electromagnetic field responsive member is provided on the first member. The first member is folded about the electromagnetic field responsive member providing opposing first proximal and first distal portions of the first member, the electromagnetic field responsive member being disposed at least partially between the opposing first proximal and first distal portions. A second member of the disposable article is provided in a folded configuration juxtaposed at least a portion of the first member to form a laminate including the first member and the second member. An electromagnetic field is applied across at least a portion of the laminate to heat the electromagnetic field responsive member to a temperature which joins at least a portion of the first member and at least a portion of the second member.

Abstract: The present invention relates to an article comprising a first pouch made of a water-reactive material, which comprises a) a first solid or liquid composition; and b) a second pouch made of a water-reactive material, comprising in its interior a second solid or liquid composition. Also provided are processes for making such article. Alternatively, the second pouch is preferably joined to the first pouch side-by-side. Preferred articles comprise fabric cleaning compositions for laundry, dish washing or hard surface cleaning or fabric care compositions.

Abstract: The present application relates to a method of softening soil deposited on a hard surface. The method comprises contacting a hard surface having soil with a composition having a soil softening additive incorporated into the composition. The compositions may be formulated at either high or low pH and preferred soil softening additives are amylase enzymes.

Abstract: The present invention provides a semi-enclosed applicator for distributing a substance onto a target surface. The applicator has a first side, a second side, and an internal cavity between the first and second sides. The applicator further includes at least one opening, such that the internal cavity is externally accessible, and the applicator further comprises: (a) a substantially non-absorbent material on one of the first and second sides; (b) a substantially absorbent material on the other of the first and second sides; and (c) a substantially fluid-impervious barrier layer within the internal cavity adjacent the non-absorbent material. The present invention also provides a semi-enclosed applicator for distributing a substance onto a target surface, the applicator having a first side, a second side, and an internal cavity between the first and second sides.

Abstract: The present invention relates to a fabric treatment composition comprising surfactant, fabric substantive dye and dye auxiliary agent. The fabric treatment composition of the invention can be used to change, refresh or maintain the color of fabric.

Abstract: The present invention relates to shoe bags useful in laundering processes, especially for laundering of shoes, particularly leather-containing shoes, such as athletic shoes. The shoe bags of the present invention are preferably used in combination with compositions for treating one or more shoes in need of treatment, and methods and articles of manufacture employing same to treat the shoes prior to and/or during and/or after washing the shoes for imparting a desired benefit to the shoes such as cleaning and/or conditioning and/or disinfecting and/or deodorizing.

Abstract: Disclosed is a hair conditioning composition comprising: (a) a thickening polymer system selected from the group consisting of a cationic thickening polymer, a nonionic thickening polymer, and mixtures thereof; (b) cationic surfactant system selected from the group consisting of one cationic surfactant, a mixture of two or more cationic surfactants, and a mixture of a cationic surfactant and a nonionic surfactant; and (c) an aqueous carrier; wherein the composition is substantially free of a water-insoluble high melting point oily compound and an anionic compound. Preferably, the conditioning composition further contains a silicone compound selected from the group consisting of a water-soluble silicone compound, a silicone nanoemulsion with an average particle diameter of less than 220 nm, and mixtures thereof. The conditioning composition of the present invention has a suitable rheology for conditioning compositions and provides conditioning benefits.

Abstract: The crystal structures of catalytic domain of HPTPbeta, both ligand-bound and ligan-free are described. These structures are useful in computer aided drug design for identifying compounds that bind or activate HPTPbeta and thereby modulate angiogenesis mediated disorders or diseases.

Abstract: Ionic liquids suitable for use in surface or air treating compositions are disclosed. Also disclosed are ionic liquid cocktails comprising three or more different and charged ionic liquid components. Compositions or products containing ionic liquids and methods of using the same are also disclosed.

Abstract: An electric toothbrush is provided. The electric toothbrush includes an elongate body having a handle portion, a head portion having a longitudinal axis, and an elongate intermediate portion disposed between the handle portion and the head portion. The head portion has a first end that is located at a position furthest from the handle portion and a second end opposite the first end that is disposed adjacent the elongate intermediate portion. The head portion has moving bristles that are disposed in a moving portion that oscillates and a static portion that extends from adjacent the moving portion to the second end of the head portion. The moving portion is disposed at the first end of the head portion and the static portion has a plurality of static bristles arranged in plurality of tufts. A motor is disposed in the handle portion and a shaft extends from the second end of the head portion to beyond the plurality of tufts of static bristles.

Abstract: A dispensing apparatus for web materials is disclosed. The dispensing apparatus comprises a support element adapted to support a supply of web material, a first dispensing rib, a second dispensing rib opposing the first dispensing rib, and a turning rib. The first dispensing rib and the second dispensing rib define a dispensing orifice. The turning rib is disposed parallel to the dispensing orifice and occludes the dispensing orifice.

Abstract: A method for determining the probability of observing an event. The event may occur either alone or in combination with one or more other events. The method may be non-combinatorial in that it does not require a separate calculation for each simultaneously occurring event, thereby significantly reducing computation time for complex systems having multiple events. Further, the method may be numerically reversed to calculate the probability of an event occurring based upon the number of observations. The method is particularly useful for predicting availability, component failure, or the possibility of a false start in production systems.

Abstract: Personal care compositions and methods for using them are provided. More particularly, the present invention relates to branched alcohol-based (alcohol and/or its derivatives) personal care compositions and methods employing same.

Abstract: The present invention relates to compositions which comprise one or more polymer conjugates having the formula: wherein T is a heterocyclic unit which is capable of inhibiting one or more proteolytic enzymes; L is a linking group; [Poly] is a polymeric unit, i indicates the number of said heterocyclic units which comprise said conjugate and has the value of from 1 to 100; z is 0 or 1, said polymer conjugates suitable for use in preventing skin irritation resulting from exposure of the skin to body fluids, inter alia, feces, menstrual fluid. The conjugates of the present invention are useful in diapers, dressings, sanitary napkins, and the like.

Abstract: According to the present invention there is provided a hard surface cleaning composition for removing cooked-, baked-, or burnt-on food soil from cookware and table ware, having surface tension of less than 30 mN/m and comprising an organic solvent system and no more than: 0.09% by weight of the composition of ethers having molecular weight of less than 210 0.007% by weight of the composition of esters having molecular weight of less than 110 0.045% by weight of the composition of glycol ethers having molecular weight of less than 130 0.0025% by weight of the composition of ketones having molecular weight of less than 90.

Abstract: The invention provides a method for improving the dispensing of a detergent composition or component thereof, comprising a surfactant and other detergent components, by providing a detergent composition comprising an intimate mixture of the surfactant component or part thereof and a crystalline layered silicate.