Abstract: Nitric esters from derivatives of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid with the formula (I), where: ?A.ident.F, Cl or Br; X.ident.O, NH or NR (R.ident.C.sub.1 -C.sub.8 alkyl); R.sub.1 and R.sub.2 independently.ident.C.sub.1 -C.sub.8 alkyl and n is a whole number from 1 to 10. The procedure includes the condensation of 2-(2,6-diahlophenylamino) phenylacetoxyacetic acid with a compound with the formula: ##STR1## where Y.ident.OH, NH.sub.2 or NHR and Z is Cl, Br or ONO.sub.2.
Abstract: 2-[(2,6-Dichlorophenyl)amino]phenylacetoxyacetyl derivatives are disclosed which have anti-inflammatory and analgesic properties. A method for making the foregoing compounds is also disclosed wherein a 2-[(2,6-dichlorophenyl)amino]phenylacetic acid salt is reacted with a benzyl haloacetate.
Abstract: A complex of 3-methoxy-N-methylmorphinan with 7-theophyllineacetic acid (1:2) is prepared by reacting the reactive materials in a polar solvent. The complex has antitussive activity.