Abstract: A transparent, elastic, and biocompatible 1K silicone for additive manufacturing that can be printed by stereolithographic processes, includes at least 25-75% by weight of a monomeric or oligomeric dimethacrylate based on silicone or silicone urethanes having a viscosity of <100 Pa·s, 20-50% by weight of one or more monomeric/oligomeric cyclic (meth)acrylates having a viscosity of <0.5 Pa·s, 1-25% by weight of silicone oil having a viscosity of <1 Pa·s, 0.5-20% by weight of fillers with a particle size of <100 ?m, 0.1-5% by weight of one or a combination of a plurality of photoinitiators whose absorption is in the wavelength range of the laser beam or irradiation source used.

Abstract: Novel pyroglutamic acid derivatives (I), wherein R1 is —OH, —ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R2, R3 and R4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumors, bacterial, fungal or viral infections, or autoimmune diseases.

Abstract: The invention relates to a device and to a method for the production of a three-dimensional object by the consecutive layered bonding of a material that can be bonded by means of electromagnetic radiation, wherein in the so-called vat an at least n-phase system, where n>2, is present, of which at least one phase comprises the building material and at least one other a phase that cannot be mixed with the building material.

Abstract: A dental modal for making a dental prosthesis has a base body formed with model teeth and model gingiva and with a cutout in an edentate area and with a hole in a floor of the cutout. A plate is releasably fittable complementarily in the cutout and is formed with a hole aligned with the hole of the cutout. A gingiva mask is fittable on the plate in the cutout and is in turn formed with a hole aligned with the holes of the plate and of the cutout. A model implant insert is releasably fittable in the holes of the mask, plate, and cutout and carries a model implant or an implant-screw mockup.

Abstract: Novel pyroglutamic acid derivatives (I), wherein R1 is —OH, —ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R2, R3 and R4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumors, bacterial, fungal or viral infections, or autoimmune diseases.

Abstract: A device whose main part is a catheter or probe which is advantageously made up by an echogenic tube on its whole length, and which is proportionally transparent. The structure is made up by a material chosen from among the group comprising amorphous thermoplastic polymer matrices incorporating a braid, strand or strip with a non metal echogenic material which is biocompatible and chosen from among filled or un-filled semi-crystalline thermoplastic polymers.

Abstract: Novel pyroglutamic acid derivatives (I), wherein R1 is —OH, —ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R2, R3 and R4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumours, bacterial, fungal or viral infections, or autoimmune diseases.

Abstract: Novel pyroglutamic acid derivatives (I), wherein R1 is ?OH, ?ORa, wherein Ra is alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl or heterocyclyl; R2, R3 and R4 are independently H, a nitrogen protecting group which hydrolyzes under acidic conditions or phtalamide; X is a pharmaceutically acceptable anion; and Y is a N-containing group; either in the form of their isolated optically active stereoisomers or in the form of mixtures thereof, are useful compounds for enhancing an immuneresponse in a subject and/or for treating tumours, bacterial, fungal or viral infections, or autoimmune diseases.

Abstract: The present invention relates to an echogenic and/or radio-opaque device adapted to permit carrying out removals from the genital organs for analysis, or adapted to promote the transfer of products, particularly gametes or embryos, into the female genital organs, or again adapted to carry out tests for the introduction of catheters into the uterus and to analyze the morphology of the neck of the uterus and of the uterine cavity, the device being characterized in that the device contains an echogenic and/or radio-opaque material permitting visualizing by medical imagery, particularly by echography or radiography, the position of the usable orifice or of the distal portion of the device.

Abstract: An echogenic and/or radio-opaque device adapted to permit carrying out removals from the genital organs for analysis, or adapted to promote the transfer of products, particularly gametes or embryos, into the female genital organs, or again adapted to carry out tests for the introduction of catheters into the uterus and to analyze the morphology of the neck of the uterus and of the uterine cavity. The device comprises an echogenic and/or radio-opaque material permitting visualizing by medical imagery, particularly by echography or radiography, the position of the usable orifice or of the distal portion of the device.