Patents Assigned to Prodotti Chimici E Alimentari S.P.A.
  • Polymorphic form of sodium hyodeoxycholate (NaHDC) and its preparation process
    Patent number: 9580458
    Abstract: The object of the present invention is a new anhydrous polymorphic crystalline form of sodium hyodeoxycholate (NaHDC) named as form II (FII) and the process for preparing it. Such a process makes it possible to obtain sodium hyodeoxycholate in the anhydrous polymorphic form II (FII), with high chemical and polymorphic purity. The invention also describes the anhydrous polymorphic crystalline forms of NaHDC named as form I (FI) and form III (Fill), the hydrated forms of NaHDC named as SI and SII, crystalline forms of NaHDC, respectively hydrated with four and eight water molecules and the amorphous form.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: February 28, 2017
    Assignee: PRODOTTI CHIMICI E ALIMENTARI S.P.A.
    Inventors: Gianluca Galdi, Paolo Sacco, Valeria Ferrari
  • POLYMORPHIC FORM OF SODIUM HYODEOXYCHOLATE (NAHDC) AND ITS PREPARATION PROCESS
    Publication number: 20160222053
    Abstract: The object of the present invention is a new anhydrous polymorphic crystalline form of sodium hyodeoxycholate (NaHDC) named as form II (FII) and the process for preparing it. Such a process makes it possible to obtain sodium hyodeoxycholate in the anhydrous polymorphic form II (FII), with high chemical and polymorphic purity. The invention also describes the anhydrous polymorphic crystalline forms of NaHDC named as form I (FI) and form III (Fill), the hydrated forms of NaHDC named as SI and SII, crystalline forms of NaHDC, respectively hydrated with four and eight water molecules and the amorphous form.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 4, 2016
    Applicant: PRODOTTI CHIMICI E ALIMENTARI S.P.A.
    Inventors: Gianluca Galdi, Paolo Sacco, Valeria Ferrari
  • Purification of tauroursodesoxycholic acid dihydrate
    Patent number: 5260462
    Abstract: Process for purification of tauroursodesoxycholic acid dihydrate prepared through reaction between taurine and mixed anhydride of ursodesoxycholic acid with an alkylcholoroformate using ion exchange resins.
    Type: Grant
    Filed: July 17, 1992
    Date of Patent: November 9, 1993
    Assignee: Prodotti Chimici E Alimentari S.P.A.
    Inventor: Massimo Parenti