Patents Assigned to PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE
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Publication number: 20160200664Abstract: The present patent application relates to a process for preparing cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.Type: ApplicationFiled: March 21, 2016Publication date: July 14, 2016Applicant: Produits Chimiques Auxiliaires et de SyntheseInventors: Jean-Marie Schneider, Jonathan Madec, Sergio Kreimerman, Gerard Guillamot
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Patent number: 9290439Abstract: The present patent application relates to a process for preparing, cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.Type: GrantFiled: September 9, 2013Date of Patent: March 22, 2016Assignee: Produits Chimiques Auxiliaires et de SyntheseInventors: Jean-Marie Schneider, Jonathan Madec, Sergio Kreimerman, Gerard Guillamot
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Patent number: 8853276Abstract: The invention relates to novel guanidine derivatives in the cinnamic series of general formula (I): The invention also relates to the process for preparing said guanidine derivatives and also to synthetic intermediates. Finally, the invention relates to the use of the guanidine derivatives for the preparation of compositions with anti-glycation properties, especially in cosmetology.Type: GrantFiled: September 6, 2011Date of Patent: October 7, 2014Assignee: Produits Chimiques Auxiliaires et de SyntheseInventors: Sylvain Rault, Jean Charles Lancelot, Peggy Suzanne, Anne-Sophie Voisin-Chiret, Regis Pecquet, Jean-Christophe Joseph
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Patent number: 8592601Abstract: A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.Type: GrantFiled: March 31, 2011Date of Patent: November 26, 2013Assignees: Produits Chimiques Auxiliaires et de Synthese, Universite de RouenInventors: Snella Chouippe, Jean-Marie Schneider, Guillaume Tauvel, Gerard Coquerel
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Publication number: 20130165507Abstract: The invention relates to novel guanidine derivatives in the cinnamic series of general formula (I): The invention also relates to the process for preparing said guanidine derivatives and also to synthetic intermediates. Finally, the invention relates to the use of the guanidine derivatives for the preparation of compositions with anti-glycation properties, especially in cosmetology.Type: ApplicationFiled: September 6, 2011Publication date: June 27, 2013Applicant: PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESEInventors: Sylvain Rault, Jean Charles Lancelot, Peggy Suzanne, Anne-Sophie Voisin-Chiret, Regis Pecquet, Jean-Christophe Joseph
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Publication number: 20110269798Abstract: A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.Type: ApplicationFiled: March 31, 2011Publication date: November 3, 2011Applicants: UNIVERSITE DE ROUEN, PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESEInventors: Snella CHOUIPPE, Jean-Marie SCHNEIDER, Guillaume TAUVEL, Gerard COQUEREL
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Patent number: 5417757Abstract: A liquid precursor for the production of fluorine doped tin oxide coatings including 60 to 90% by weight of at least one chlorinated organotin derivative, 5 to 30% by weight of at least one organotin mono(fluoroalkanoate), and 0 to 15% by weight of a tetraorganotin compound. Using vapor phase deposition, this produces a coating with low surface resistance and a high light transmission coefficient. Deposition is effected quickly so the precursor can readily be used to coat a moving substrate, for example, float glass.Type: GrantFiled: April 25, 1994Date of Patent: May 23, 1995Assignee: Produits Chimiques Auxiliaires Et De Synthese, (P.C.A.S.) (S.A.)Inventors: Gilles Merienne, Dominique Valette, Marcel Durant
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Patent number: 5045361Abstract: A process for producing an acrylic and/or methacrylic polymer based preparation for the surface treatment of zinc consists in polymerizing at least one (meth)acrylic acid and at least one (meth)acrylate in a mixture of organic cosolvents. The preparation is then formed from the resultant copolymer in the cosolvents by dilution in a quantity of water and preferably an excess of water with respect to the cosolvents in the polymerization stage.Type: GrantFiled: October 14, 1988Date of Patent: September 3, 1991Assignee: Produits Chimiques Auxiliaires et de Synthese (P.C.A.S.)Inventor: Jean P. Kerherve
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Patent number: 5037877Abstract: A process for producing an acrylic and/or methacrylic polymer based preparation for the surface treatment of zinc consists in polymerizing at least one (meth)acrylic acid and at least one (meth)acrylate in a mixture of organic cosolvents. The preparation is then formed from the resultant copolymer in the cosolvents by dilution in a quantity of water and preferably an excess of water with respect to the cosolvents in the polymerization stage.Type: GrantFiled: August 6, 1990Date of Patent: August 6, 1991Assignee: Produits Chimiques Auxiliaires et de Synthese (P.C.A.S.)Inventor: Jean P. Kerherve
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Patent number: 4180510Abstract: A method for preparing thienylacetic acid and its derivatives is disclosed, wherein a glyoxylic ester is made to react with hydrazine, and after with potash. Advantageously, the glyoxylic ester is prepared by condensation of a monoester monochloride of oxalic acid upon a thiophenic derivative, in the presence of titanium chloride.The so obtained products are useful as organic synthesis intermediaries for various products of pharmaceutical type.Type: GrantFiled: January 12, 1978Date of Patent: December 25, 1979Assignee: Produits Chimiques Auxiliaires et de Synthese, P.C.A.S.Inventors: Yves Le Guen, Georges Thiault