Patents Assigned to PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE
  • Publication number: 20160200664
    Abstract: The present patent application relates to a process for preparing cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.
    Type: Application
    Filed: March 21, 2016
    Publication date: July 14, 2016
    Applicant: Produits Chimiques Auxiliaires et de Synthese
    Inventors: Jean-Marie Schneider, Jonathan Madec, Sergio Kreimerman, Gerard Guillamot
  • Patent number: 9290439
    Abstract: The present patent application relates to a process for preparing, cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: March 22, 2016
    Assignee: Produits Chimiques Auxiliaires et de Synthese
    Inventors: Jean-Marie Schneider, Jonathan Madec, Sergio Kreimerman, Gerard Guillamot
  • Patent number: 8853276
    Abstract: The invention relates to novel guanidine derivatives in the cinnamic series of general formula (I): The invention also relates to the process for preparing said guanidine derivatives and also to synthetic intermediates. Finally, the invention relates to the use of the guanidine derivatives for the preparation of compositions with anti-glycation properties, especially in cosmetology.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: October 7, 2014
    Assignee: Produits Chimiques Auxiliaires et de Synthese
    Inventors: Sylvain Rault, Jean Charles Lancelot, Peggy Suzanne, Anne-Sophie Voisin-Chiret, Regis Pecquet, Jean-Christophe Joseph
  • Patent number: 8592601
    Abstract: A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: November 26, 2013
    Assignees: Produits Chimiques Auxiliaires et de Synthese, Universite de Rouen
    Inventors: Snella Chouippe, Jean-Marie Schneider, Guillaume Tauvel, Gerard Coquerel
  • Publication number: 20130165507
    Abstract: The invention relates to novel guanidine derivatives in the cinnamic series of general formula (I): The invention also relates to the process for preparing said guanidine derivatives and also to synthetic intermediates. Finally, the invention relates to the use of the guanidine derivatives for the preparation of compositions with anti-glycation properties, especially in cosmetology.
    Type: Application
    Filed: September 6, 2011
    Publication date: June 27, 2013
    Applicant: PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE
    Inventors: Sylvain Rault, Jean Charles Lancelot, Peggy Suzanne, Anne-Sophie Voisin-Chiret, Regis Pecquet, Jean-Christophe Joseph
  • Publication number: 20110269798
    Abstract: A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.
    Type: Application
    Filed: March 31, 2011
    Publication date: November 3, 2011
    Applicants: UNIVERSITE DE ROUEN, PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE
    Inventors: Snella CHOUIPPE, Jean-Marie SCHNEIDER, Guillaume TAUVEL, Gerard COQUEREL
  • Patent number: 5417757
    Abstract: A liquid precursor for the production of fluorine doped tin oxide coatings including 60 to 90% by weight of at least one chlorinated organotin derivative, 5 to 30% by weight of at least one organotin mono(fluoroalkanoate), and 0 to 15% by weight of a tetraorganotin compound. Using vapor phase deposition, this produces a coating with low surface resistance and a high light transmission coefficient. Deposition is effected quickly so the precursor can readily be used to coat a moving substrate, for example, float glass.
    Type: Grant
    Filed: April 25, 1994
    Date of Patent: May 23, 1995
    Assignee: Produits Chimiques Auxiliaires Et De Synthese, (P.C.A.S.) (S.A.)
    Inventors: Gilles Merienne, Dominique Valette, Marcel Durant
  • Patent number: 5045361
    Abstract: A process for producing an acrylic and/or methacrylic polymer based preparation for the surface treatment of zinc consists in polymerizing at least one (meth)acrylic acid and at least one (meth)acrylate in a mixture of organic cosolvents. The preparation is then formed from the resultant copolymer in the cosolvents by dilution in a quantity of water and preferably an excess of water with respect to the cosolvents in the polymerization stage.
    Type: Grant
    Filed: October 14, 1988
    Date of Patent: September 3, 1991
    Assignee: Produits Chimiques Auxiliaires et de Synthese (P.C.A.S.)
    Inventor: Jean P. Kerherve
  • Patent number: 5037877
    Abstract: A process for producing an acrylic and/or methacrylic polymer based preparation for the surface treatment of zinc consists in polymerizing at least one (meth)acrylic acid and at least one (meth)acrylate in a mixture of organic cosolvents. The preparation is then formed from the resultant copolymer in the cosolvents by dilution in a quantity of water and preferably an excess of water with respect to the cosolvents in the polymerization stage.
    Type: Grant
    Filed: August 6, 1990
    Date of Patent: August 6, 1991
    Assignee: Produits Chimiques Auxiliaires et de Synthese (P.C.A.S.)
    Inventor: Jean P. Kerherve
  • Patent number: 4180510
    Abstract: A method for preparing thienylacetic acid and its derivatives is disclosed, wherein a glyoxylic ester is made to react with hydrazine, and after with potash. Advantageously, the glyoxylic ester is prepared by condensation of a monoester monochloride of oxalic acid upon a thiophenic derivative, in the presence of titanium chloride.The so obtained products are useful as organic synthesis intermediaries for various products of pharmaceutical type.
    Type: Grant
    Filed: January 12, 1978
    Date of Patent: December 25, 1979
    Assignee: Produits Chimiques Auxiliaires et de Synthese, P.C.A.S.
    Inventors: Yves Le Guen, Georges Thiault