Abstract: Certain embodiments are directed to recombinant vesiculovirus encoding a heterologous polynucleotide and methods of using the same.
Type:
Grant
Filed:
February 27, 2015
Date of Patent:
April 3, 2018
Assignees:
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, PROFECTUS BIOSCIENCES, INC.
Inventors:
Demetrius Matassov, Rodion V. Gorchakov, Stefan Hamm, Rebecca Nowak, Robert L. Seymour, John H. Eldridge, Robert B. Tesh, David K. Clarke, Theresa E. Latham, Scott Weaver, Farooq Nasar
Abstract: The invention relates to compounds of formulae (1) and (2): and pharmaceutically acceptable salts thereof for the treatment of cancer, inflammation, auto-immune diseases, diabetes and diabetic complications, infection, cardiovascular disease and ischemia-reperfusion injuries.
Type:
Grant
Filed:
March 25, 2010
Date of Patent:
January 14, 2014
Assignee:
Profectus Biosciences, Inc.
Inventors:
Jie Zhang, Drago Robert Sliskovic, Charles E. Ducker
Abstract: The invention relates to compounds of formula (I), formula (II), formula (III) and formula (IV), and pharmaceutically acceptable salts thereof for the treatment of cancer, inflammation, auto-immune diseases, diabetes and diabetic complications, infection, cardiovascular disease and ischemia-reperfusion injuries.
Type:
Application
Filed:
June 16, 2010
Publication date:
April 12, 2012
Applicant:
Profectus Biosciences, Inc.
Inventors:
Jie Zhang, Drago Robert Sliskovic, Charles E. Ducker
Abstract: The invention relates to compounds of formula (1) and formula (2), and pharmaceutically acceptable salts thereof for the treatment of cancer, inflammation, auto-immune diseases, diabetes and diabetic complications, infection, cardiovascular disease and ischemia-reperfusion injuries, wherein R1 is defined herein.
Type:
Application
Filed:
April 29, 2010
Publication date:
February 23, 2012
Applicant:
Profectus Biosciences, Inc.
Inventors:
Jie Zhang, Drago Robert Sliskovic, Charles E. Ducker
Abstract: The invention relates to compounds of formulae (1) and (2): and pharmaceutically acceptable salts thereof for the treatment of cancer, inflammation, auto-immune diseases, diabetes and diabetic complications, infection, cardiovascular disease and ischemia-reperfusion injuries.
Type:
Application
Filed:
March 25, 2010
Publication date:
January 19, 2012
Applicant:
Profectus Biosciences, Inc.
Inventors:
Jie Zhang, Drago Robert Sliskovic, Charles E. Ducker