Abstract: The endocervical instrument of this invention comprises, generally, a handle and an elongated basket-like member removably mounted onto the handle. The basket-like member is elongated and generally of rectangular-shape as viewed in plan. The basket member has a wall surface defining an elongated cavity therewithin and an entrance into the cavity from one side of the basket member. One end of the basket member carries a blade means which preferably projects laterally with respect to the entrance to the elongated cavity of the basket member. The blade member projects laterally from the sidewalls defining the entrance to the cavity a sufficient distance to enable an endocervical tissue strip of approximately 1.5-2 mm., in depth, to be obtained as the blade member is drawn distally towards the external os of the endocervical canal.

Abstract: This invention is directed to a method and means for the early detection of a wide variety of cancers, in humans, which method and means consists of the assay and development of a pattern or fingerprint of severally biologically inert, or inactive polypeptides (or perhaps biologically active peptides) in the blood of humans, e.g.: big-ACTH (big-Adrenocorticotropin Hormone), big-.beta.MSH (big-beta melanocyte-stimulating Hormone), the alpha chain of the glycopeptide hormones, the measurement of the arginine vasotocin (AVT), an analogue of Arginine vasopressin, (AVP) (or the combined measurement of AVP and AVT). The values obtained by the assays of each of the foregoing polypeptids is then compared with the individual values and patterns found in humans. If any one of the polypeptide values is elevated above the upper end of the normal values, a carcinoma from some tumor site is suspected; also from the pattern of elevations in one or more peptides, a specific type of cancer may be suspected.

Abstract: A method of immunization of human males to achieve contraception is provided which includes the step of administering, periodically, predetermined amounts of, non-primate, highly purified FSH having a biologic potency of at least 1,000 I.U. (International Units)/mg, an LH contamination of below 11 I.U./mg and a TSH contamination of less than 0.1 I.U./mg, to a human male until his sperm production declines below about twenty million per cc. FSH is the Follicle Stimulating Hormone; LH the Luteinizing Hormone; and TSH the Thyroid Stimulating Hormone.