Patents Assigned to Profounda, Inc
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Patent number: 11167079Abstract: A cartridge for delivery of a material therefrom which has a corrugated portion to allow for bending/extending to be applied to the device from which a material to be deposited can be dispensed. The bendability and extendibility allow for greater efficiency in use and application of the material into cavities, pockets, and/or crevices where one needs to deposit the material.Type: GrantFiled: May 14, 2018Date of Patent: November 9, 2021Assignee: Profounda, Inc.Inventors: Todd Ewen MacLaughlan, Vinit Gopal Kathardekar, Amanullah Abdulhamid Vazir
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Patent number: 10806741Abstract: Methods of treating infections caused by free-living amoeba are disclosed. The methods generally include systemic administration of an effective amount of miltefosine, such as an oral or intravenous formulation, and optionally local administration of an effective amount of miltefosine, such as a topical formulation of miltefosine. The methods may further include administration of one or more secondary agents. Exemplary secondary agents include steroids, polyhexamethylene biguanide (PHMB), chlorhexidine, propamidine isethionate, dibromopropamidine isethionate, neomycin, paromomycin, polymyxin B, clotrimazole, ketoconazole, miconazole, and itraconazole. The methods may be used to treat patients with infections caused by a free-living amoeba such as Naegleria fowleri, Balamuthia mandrillaris, Sappinia diploidea, and Acanthamoeba species.Type: GrantFiled: July 18, 2019Date of Patent: October 20, 2020Assignee: Profounda, Inc.Inventor: Todd Ewen MacLaughlan
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Publication number: 20200093842Abstract: Methods of treating infections caused by free-living amoeba are disclosed. The methods generally include systemic administration of an effective amount of miltefosine, such as an oral or intravenous formulation, and optionally local administration of an effective amount of miltefosine, such as a topical formulation of miltefosine. The methods may further include administration of one or more secondary agents. Exemplary secondary agents include steroids, polyhexamethylene biguanide (PHMB), chlorhexidine, propamidine isethionate, dibromopropamidine isethionate, neomycin, paromomycin, polymyxin B, clotrimazole, ketoconazole, miconazole, and itraconazole. The methods may be used to treat patients with infections caused by a free-living amoeba such as Naegleria fowleri, Balamuthia mandrillaris, Sappinia diploidea, and Acanthamoeba species.Type: ApplicationFiled: July 18, 2019Publication date: March 26, 2020Applicant: Profounda, Inc.Inventor: Todd Ewen MACLAUGHLAN
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Publication number: 20180370663Abstract: A device for filling a container, such as a dispensing tip, with a powdered or liquid material, and methods of use of the device are disclosed. The device generally includes a vacuum manifold having at least one port, and a vacuum source for creating a negative pressure in the vacuum manifold. The device may further include at least one container having an axial bore therethrough, a proximal end, and a distal end which includes a stop positioned therein. The negative pressure created in the vacuum manifold by the vacuum pump is sufficient to pull the powdered or liquid material through the distal end into the axial bore of the at least one container. A clearance between an outer surface of the stop and an inner wall of the container is configured to prevent passage of the powdered or liquid material.Type: ApplicationFiled: June 27, 2018Publication date: December 27, 2018Applicant: Profounda, Inc.Inventor: Todd Ewen MacLaughlan
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Publication number: 20180256809Abstract: A cartridge for delivery of a material therefrom which has a corrugated portion to allow for bending/extending to be applied to the device from which a material to be deposited can be dispensed. The bendability and extendibility allow for greater efficiency in use and application of the material into cavities, pockets, and/or crevices where one needs to deposit the material.Type: ApplicationFiled: May 14, 2018Publication date: September 13, 2018Applicant: Profounda, Inc.Inventors: Todd Ewen MacLaughlan, Vinit Gopal Kathardekar, Amanullah Abdulhamid Vazir
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Patent number: 10034974Abstract: A cartridge for delivery of a material therefrom which has a corrugated portion to allow for bending/extending to be applied to the device from which a material to be deposited can be dispensed. The bendability and extendibility allow for greater efficiency in use and application of the material into cavities, pockets, and/or crevices where one needs to deposit the material.Type: GrantFiled: July 29, 2016Date of Patent: July 31, 2018Assignee: ProFounda, Inc.Inventors: Todd Ewen MacLaughlan, Vinit Gopal Kathardekar, Amanullah Abdulhamid Vazir
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Publication number: 20160331889Abstract: A cartridge for delivery of a material therefrom which has a corrugated portion to allow for bending/extending to be applied to the device from which a material to be deposited can be dispensed. The bendability and extendibility allow for greater efficiency in use and application of the material into cavities, pockets, and/or crevices where one needs to deposit the material.Type: ApplicationFiled: July 29, 2016Publication date: November 17, 2016Applicant: Profounda, Inc.Inventors: Todd Ewen MacLaughlan, Vinit Gopal Kathardekar, Amanullah Abdulhamid Vazir
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Patent number: 9402701Abstract: A cartridge for delivery of a material therefrom which has a corrugated portion to allow for bending/extending to be applied to the device from which a material to be deposited can be dispensed. The bendability and extendibility allow for greater efficiency in use and application of the material into cavities, pockets, and/or crevices where one needs to deposit the material.Type: GrantFiled: October 22, 2013Date of Patent: August 2, 2016Assignee: Profounda, IncInventors: Todd Ewen MacLaughlan, Vinit Gopal Kathardekar, Amanullah Abdulhamid Vazir