Patents Assigned to Progen Pharmaceuticals Limited
  • Patent number: 8828952
    Abstract: The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment of a mammalian subject.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: September 9, 2014
    Assignee: Progen Pharmaceuticals Limited
    Inventors: Vito Ferro, Tomislav Karoli, Ligong Liu, Paul Newton Handley, Kenneth David Johnstone, Norbert Wimmer, Edward Timothy Hammond
  • Patent number: 8173606
    Abstract: The invention relates to compounds which are polysulfated oligosaccharide derivatives having activity as inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; methods for the preparation of the compounds; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease of a mammalian subject.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: May 8, 2012
    Assignee: Progen Pharmaceuticals Limited
    Inventors: Vito Ferro, Jon Krueger Fairweather, Tomislav Karoli, Ligong Liu
  • Publication number: 20110130354
    Abstract: The invention relates to compounds which are polysulfated oligosaccharide derivatives having activity as inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; methods for the preparation of the compounds; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease of a mammalian subject.
    Type: Application
    Filed: December 3, 2010
    Publication date: June 2, 2011
    Applicant: Progen Pharmaceuticals Limited
    Inventors: Vito Ferro, Jon Krueger Fairweather, Tomislav Karoli, Ligong Liu
  • Patent number: 7875592
    Abstract: The invention relates to compounds which are polysulfated oligosaccharide derivatives having activity as inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; methods for the preparation of the compounds; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease of a mammalian subject.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: January 25, 2011
    Assignee: Progen Pharmaceuticals Limited
    Inventors: Vito Ferro, Jon Krueger Fairweather, Tomislav Karoli, Ligong Liu