Abstract: Prader-Willi Syndrome is alleviated by administering of a 3-oxo or hydroxy substituted 5-beta-androstan-17-one to an individual having the syndrome.
Type:
Grant
Filed:
July 24, 1989
Date of Patent:
April 9, 1991
Assignees:
Progenics, Inc., Long Island Jewish Medical Center
Abstract: Methods and compositions are disclosed for inducing an incresed blood level of alpha-etiocholanolone in the body of a mammal in need of such treatments comprising administering to said mammal an amount of etiocholanedione effective to induce said increased blood level.
Abstract: 16-Alkylated and 16-alkylated-7-hydroxy 5.beta.-androstan-3-ol-17-one, and the esters and ethers thereof, are used as an anti-diabetic, anti-obesity and erythropoietic agent in mammals.
Abstract: 5-.beta.-androstandione is produced in high yield by contacting androstendione with a palladium catalyst and thereafter recovering the 5-.beta.-androstandione thus produced.
Abstract: Diabetes obesity syndromes and associated hypercorticoidism are treated with a synergistic combination of .alpha.- and/or .beta.-etiocholanolone and an estrogen.
Type:
Grant
Filed:
December 28, 1983
Date of Patent:
March 26, 1985
Assignees:
Progenics, Inc., The Jackson Laboratory