Abstract: Methods for identifying ubiquitin ligases and ubiquitin ligase modulators are disclosed. The methods comprise combining the components of a ubiquitylation reaction and using proteins that contain motifs that recognize ubiquitylated sites in the detection of ubiquitylation.
Type:
Application
Filed:
July 23, 2009
Publication date:
January 28, 2010
Applicant:
PROGENRA, INCORPORATED
Inventors:
Jeffrey Gordon Marblestone, Suresh Kumar Kizhakkethil-George, Benjamin Nicholson