Abstract: Exothermic and/or endothermic chemical reactions in combination with phase change materials can produce output temperature(s) within strict tolerances without requiring expensive and complicated external equipment to generate and maintain an output temperature. Similarly, an exothermic phase change material, which generates heat as a consequence of crystallizing a supercooled liquid, can generate heat at a constant temperature, without requiring expensive and complicated external equipment, as a consequence of the liquid form of the exothermic phase change material being in equilibrium with the solid form of the exothermic phase change material. Numerous biological and chemical processes and/or diagnostic devices require a constant temperature or temperatures for set periods of time.

Abstract: Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training.

Abstract: Exothermic and/or endothermic chemical reactions in combination with phase change materials can produce output temperature(s) within strict tolerances without requiring expensive and complicated external equipment to generate and maintain an output temperature. Similarly, an exothermic phase change material, which generates heat as a consequence of crystallizing a supercooled liquid, can generate heat at a constant temperature, without requiring expensive and complicated external equipment, as a consequence of the liquid form of the exothermic phase change material being in equilibrium with the solid form of the exothermic phase change material. Numerous biological and chemical processes and/or diagnostic devices require a constant temperature or temperatures for set periods of time.

Abstract: The present invention is directed to microbicidal compositions and methods of use thereof for preventing the transmission of or treating sexually transmitted infections and/or common vaginal infections, while minimizing disruptions to vaginal ecology. The microbicidal compositions of the present invention comprise the microbicidal agent bisabolol. In a further embodiment of the present invention, the microbicidal agent may comprise a combination of bisabolol and Ciclopirox Olamine. These compositions are preferably encapsulated in the form of a foam, cream, wash, gel, suppository, ovule, ointment, film, tablet, foaming tablet, tampon, vaginal spray, or aerosol. The concentration of microbicidal agent will vary depending on the base or carrier. Preferably the concentration will fall within the parameters of approximately 0.01% to approximately 50% by weight, more preferably between approximately 0.01% to approximately 28%, and most preferably between approximately 0.05% and approximately 2%.

Abstract: A visual cervical inspection apparatus for visual inspection of a cervix has a housing having a cavity. The housing has a proximal viewing aperture located in a proximal end of the housing and a distal aperture at a distal end of the housing. A light source is attached to the housing and is adapted to illuminate the cervix with light sufficient to visibly enhance the definition between cancerous and healthy cervical tissue. Magnification optics are disposed within the cavity of the housing which provide for magnified viewing of the illuminated cervix. The visibly enhanced definition between cancerous and healthy cervical tissue can thus be more easily viewed by a user of the visual cervical inspection apparatus. Light emitting diodes of the appropriate light wavelength can be used to provide the necessary illumination of the cervix. Krypton, xenon or other similar bulbs may also be used when filtered to produce light of approximately between 480-580 nanometers.

Abstract: A single use syringe including a mechanical means permitting a single withdrawal of the plunger to load the cylinder an a single advance of the plunger to inject the material, thereafter incapacitating the mechanism. The mechanical means may well be retrofit to existing syringes.