Patents Assigned to Prolor Biotech Ltd.
  • Long-acting veterinary polypeptides and methods of producing and administering same
    Patent number: 8465948
    Abstract: A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: June 18, 2013
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting growth hormone and methods of producing same
    Patent number: 8450269
    Abstract: Use of a growth hormone protein and polynucleotides encoding same comprising an amino-terminal carboxy-terminal peptide (CTP) of chorionic gonadotrophin and two carboxy-terminal chorionic gonadotrophin CTPs attached to the growth hormone in methods of inducing growth or weight gain, method of increasing insulin-like growth factor (IGF-1) levels, and methods of reducing the dosing frequency of a growth hormone in a human subject are disclosed. Pharmaceutical compositions comprising the growth hormone and polynucleotides encoding the growth hormone of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: May 28, 2013
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting interferons and derivatives thereof and methods thereof
    Patent number: 8323636
    Abstract: A polypeptide and polynucleotides encoding same comprising carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an IFN protein are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: December 4, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting veterinary polypeptides and methods of producing and administering same
    Patent number: 8114836
    Abstract: A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: February 14, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting EPO polypeptides and derivatives thereof and methods thereof
    Patent number: 8110376
    Abstract: A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an EPO peptide are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: February 7, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Polynucleotides encoding long-acting growth hormone polypeptides and methods of producing same
    Patent number: 8097435
    Abstract: A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a peptide-of-interest are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: January 17, 2012
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima
  • Long-acting interferons and derivatives thereof and methods thereof
    Patent number: 8048848
    Abstract: A polypeptide and polynucleotides encoding same comprising carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to an IFN protein are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: November 1, 2011
    Assignee: Prolor Biotech Ltd.
    Inventors: Fuad Fares, Udi Eyal Fima