Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Grant
Filed:
July 10, 2014
Date of Patent:
July 19, 2016
Assignee:
PRONAI THERAPEUTICS, INC.
Inventors:
Gholamreza Sheikhnehjad, Mina Patel Sooch, Neal Goodwin, David Olson
Abstract: The invention relates to compositions and methods to inhibit gene expression. In particular, the invention provides co-therapies comprising oligonucleotides plus other therapies to treat cancer.
Type:
Grant
Filed:
March 23, 2012
Date of Patent:
September 2, 2014
Assignee:
ProNAi Therapeutics, Inc.
Inventors:
Neal Clifford Goodwin, James Patrick McGovren
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Grant
Filed:
June 1, 2005
Date of Patent:
August 26, 2014
Assignee:
ProNAi Therapeutics, Inc.
Inventors:
Gholamreza Sheikhnehjad, Mina Patel Sooch, Neal Clifford Goodwin, David Olson
Abstract: The invention relates to compositions and methods to inhibit gene expression. In particular, the invention provides DNAi oligonucleotides sequestered by amphoteric liposomes for the treatment of cancer.
Abstract: The invention relates to compositions and methods to inhibit gene expression. In particular, the invention provides DNAi oligonucleotides sequestered by amphoteric liposomes for the treatment of cancer.
Abstract: The invention relates to compositions and methods to inhibit gene expression. In particular, the invention provides co-therapies comprising oligonucleotides plus other therapies to treat cancer.
Type:
Application
Filed:
March 23, 2012
Publication date:
November 22, 2012
Applicant:
ProNAi Therapeutics,Inc.
Inventors:
Neal Clifford Goodwin, J. Patrick McGovren
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Application
Filed:
June 1, 2005
Publication date:
June 9, 2011
Applicant:
PRONAI THERAPEUTICS, INC.
Inventors:
Gholamreza Sheikhnehjad, Mina Patel Sooch, Neal Goodwin, David Olson
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Grant
Filed:
September 22, 2005
Date of Patent:
October 5, 2010
Assignee:
ProNAI Therapeutics, Inc.
Inventors:
Gholamreza Sheikhnejad, Neal Goodwin, David Olson
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Grant
Filed:
June 1, 2004
Date of Patent:
March 3, 2009
Assignee:
ProNAI Therapeutics, Inc.
Inventors:
Gholamreza Sheikhnehjad, Mina Patel Sooch, Neal Goodwin, David Olson
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Application
Filed:
June 1, 2004
Publication date:
September 7, 2006
Applicant:
ProNAi Therapeutics, Inc.
Inventors:
Gholamreza Sheikhnejad, Mina Sooch, Neal Goodwin, David Olson
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Application
Filed:
June 1, 2004
Publication date:
April 6, 2006
Applicant:
ProNAi Therapeutics, Inc.
Inventors:
Gholamreza Sheikhnehjad, Mina Sooch, Neal Goodwin, David Olson
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Application
Filed:
June 1, 2004
Publication date:
December 29, 2005
Applicant:
ProNAi Therapeutics, Inc.
Inventors:
Reza Sheikhnejad, Mina Sooch, Neal Goodwin, David Olson